Found 477 clinical trials
Clinical Study of CLL1 CAR-T Cells in the Treatment of Hematological Malignancies
Clinical Study on the Safety and Effectiveness of CLL1 CAR-T Cells in the Treatment of CLL1-positive Hematological Malignancies
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- 15 Mar, 2022
- 2 locations
A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of nemtabrutinib in Japanese participants with mature B-cell neoplasms.
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- 04 Sep, 2023
- 7 locations
A Study of GNC-035 in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematological Malignancies
antibody injection in patients with relapsed or refractory chronic lymphocytic leukemia and other hematological malignancies
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- 18 Sep, 2023
- 1 location
Efficacy and Safety of Micafungin for Injection in Prevention and Treatment of Fungal Infection in Hematological Tumors
patients with hematological tumors.
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- 15 Feb, 2021
- 1 location
VEN-OM: Phase IB/II Study Of Safety And Efficacy Of Venetoclax When Combined With Escalating Doses Of Omacetaxine In Patients With Relapsed/Refractory Hematologic Malignancies Failing Treatment With Venetoclax-Containing Regimens (VEN-OM)
participants with relapsed/refractory hematologic malignancies including those failing treatment with venetoclax-containing regimens. Treatment plan will consist of an induction phase, followed by a
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- 13 Oct, 2022
- 1 location
Antimicrobial Revision in Persistent Febrile Neutropenia
Febrile neutropenia is often seen in patients with hematologic malignancies who receive cytotoxic chemotherapy. These patients are usually placed on posaconazole prophylaxis upon starting
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- 21 Sep, 2023
- 1 location
4SCAR19U T Cells Targeting B Cell Malignancies
The purpose of this study is to assess the feasibility, safety and efficacy of universal CAR T cell therapy against CD19-positive hematological malignancies using a novel CD19-specific CAR T
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- 23 Aug, 2023
- 2 locations
Clinical Study of Hospital-manufactured CD19 CAR-T in Children and Adolescents With Acute Lymphoblastic Leukemia
Chimeric antigen receptor T cells (CAR-T cells) have been developed to treat relapsed and refractory hematological malignancies with promising outcome in patients with very poor prognosis. The
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- 14 Mar, 2022
- 1 location
Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study
develop blood cancers in the future. This transformation from low blood cell counts to cancer may be caused by inflammation in the body. Canakinumab is a monoclonal antibody that may block inflammation in
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- 11 Apr, 2023
- 1 location
Sequential Analysis in Patients With an Hemopathy
Recent advances in hematology clearly illustrate that the simple "clonal" nature of various hematological malignancies may not really reflect the reality of malignant cells natural expansion
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- 21 Jan, 2021