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Found 568 clinical trials
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Study of Tinostamustine First-in-Class Alkylating HDACi Fusion Molecule in Relapsed/Refractory Hematologic Malignancies

This study evaluates the efficacy, safety and pharmacokinetics of tinostamustine (EDO-S101) in patients with relapsed/refractory hematologic malignancies. All patients will receive

hematologic malignancy
refractory peripheral t-cell lymphoma
hodgkin's disease
sezary syndrome
peripheral t-cell lymphoma
  • 0 views
  • 14 Jun, 2021
  • 26 locations
None
TRial to EvaluAte Tranexamic Acid Therapy in Thrombocytopenia

The purpose of this study is to test whether giving tranexamic acid to patients receiving treatment for blood cancers reduces the risk of bleeding or death, and the need for platelet

hematologic malignancy
cancer
tranexamic acid
cell transplantation
  • 682 views
  • 29 Sep, 2021
  • 28 locations
None
Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older Medically Infirm or Frail Patients With Blood Diseases

This phase II/III trial studies the best approach in improving quality of life and survival after a donor stem cell transplant in older, weak, or frail patients with blood diseases. Patients who have undergone a transplant often experience increases in disease and death. One approach, supportive and palliative care (SPC), …

cancer
blood disorder
hematologic disorders
cell transplantation
  • 3 views
  • 20 Oct, 2021
  • 12 locations
None
Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

This is an open-label, multi-center Phase 1 study of LY3410738, an oral, covalent IDH inhibitor, in patients with IDH1 and/or IDH2-mutant advanced hematologic malignancies who have received

blast cells
IDH2
hematologic malignancy
  • 0 views
  • 20 Oct, 2021
  • 49 locations
None
A Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic Malignancies

pharmacokinetic (PK) profile of ABBV-621 for participants with previously-treated solid tumors or hematologic malignancies.

solid tumour
hodgkin's disease
KRAS
leukemia
solid tumor
  • 242 views
  • 02 Jun, 2021
  • 25 locations
None
Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant

This phase III trial investigates health informatics and a self-management program for improving the health of cancer survivors after stem cell transplant. After transplant many survivors may feel stressed or may be unsure of what health care they need. A self-management program called "INSPIRE," along with a personalized survivorship care …

remission
cancer
  • 73 views
  • 21 Oct, 2021
  • 17 locations
None
Impact of Phone Call About Financial Reimbursement Program on Access to Cancer Clinical Trials

This trial studies how well a follow-up phone call regarding financial reimbursement program (FRP) works in improving cancer patients' access to therapeutic cancer clinical trials. Follow-up phone call intervention regarding FRP may improve recruitment of cancer patients to cancer therapeutic clinical trials.

cancer diagnosis
primary cancer
  • 2 views
  • 27 Jan, 2021
  • 3 locations
None
Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses

This clinical trial examines a financial navigation program in helping patients and their spouses understand and better manage the financial aspects of cancer care. Cancer patients and their spouses may be at high risk for financial problems because of the cost of cancer treatment. A financial navigator is a person …

cancer
solid tumor
bone marrow transplant
experimental drug
  • 0 views
  • 08 Sep, 2021
  • 65 locations
None
Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

This study will evaluate the safety and efficacy of favezelimab in combination with pembrolizumab (MK-3475) in participants with hematological malignancies: classical Hodgkin

diffuse large b-cell lymphoma
classical hodgkin lymphoma
hodgkin's disease
pembrolizumab
mk-3475
  • 45 views
  • 17 Oct, 2021
  • 25 locations
None
A Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies

This is a phase 1, 2-part, global, multicenter, open-label, PK, safety and tolerability study of oral tazemetostat in subjects with either advanced solid tumors, or hematological malignancies

solid tumour
malabsorption syndrome
cancer
serum pregnancy test
renal function
  • 17 views
  • 02 Jun, 2021
  • 13 locations