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Found 598 clinical trials
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SARS-CoV-2 Donor-Recipient Immunity Transfer

This study investigates whether donors with previous exposure to COVID-19 can pass their immunity by hematopoietic (blood) stem cell transplant (HCT) donation to patients that have not been exposed. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the COVID19 infection. This study may provide critical information …

granulocyte colony stimulating factor
cyclophosphamide
lymphoma
myelofibrosis
mobilized
  • 0 views
  • 02 Sep, 2021
  • 1 location
None
Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma

with complementary drugs lenalidomide (Revlimid) and pomalidomide (Pomalyst) can help in haematological malignancy treatment. In order to do this there is the need to see how the cancer cells respond

pomalidomide
leukemia
pomalyst
cancer
revlimid
  • 0 views
  • 26 Nov, 2021
  • 1 location
None
CHIP/CCUS Natural History Protocol

Background Clonal Hematopoiesis of Indeterminate Potential (CHIP) is a change in a person s DNA that can increase a person s risk of developing blood cancers or

  • 0 views
  • 30 Nov, 2021
  • 1 location
None
A Non-Interventional National Study in Pediatric Patients With Unexplained Enlarged Spleen

(e.g. portal hypertension, haematological malignancy, hemolytic anemia, infection) based on clinical examination and routine biological tests (full blood count, reticulocytes, liver tests, abdominal

  • 0 views
  • 23 Nov, 2021
  • 1 location
None
Immune Response to SARS-CoV-2 (COVID-19) Vaccines in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

lymphoma (SLL). CLL and SLL are types of blood cancer that begin in cells of the immune system. CLL/SLL and the medications used to treat these conditions may change the way vaccines work in a patient's

chronic lymphocytic leukemia
lymphoma
cancer
  • 0 views
  • 24 Nov, 2021
  • 20 locations
None
Allo-HSCT as First-line Consolidation in High-risk PTCL

is the availability of a HLA matched donors. Haploidentical family donors have been successfully used in treatments of hematologic malignancies, including malignant lymphomas. Thus, allo-HSCT could

t-cell lymphoma
cancer
stem cell transplantation
cell transplantation
peripheral t-cell lymphoma
  • 2 views
  • 25 Jan, 2021
  • 1 location
None
A Non-Interventional National Study in Pediatric Patients With Unexplained Enlarged Spleen

(e.g. portal hypertension, haematological malignancy, hemolytic anemia, infection) based on clinical examination and routine biological tests (full blood count, reticulocytes, liver tests, abdominal

  • 0 views
  • 10 Nov, 2021
  • 2 locations
None
NGS-based Comprehensive Genomic ctDNA Panel in NSCLC With Immunotherapy

tumor DNA (ctDNA) assay has the considerable potential to detect the blood tumor mutation burden (bTMB), and bTMB calculated by ctDNA assay is regarded as a novel and promising biomarker for

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Haploidentical Peripheral Blood Stem Cell Transplantation for Acute Leukemia

Allogeneic stem cell transplantation (Allo-HSCT) is the effective and even the only treatment for hematological malignancies. The "GIAC" protocol established by our center has successfully

cancer
antibiotics
remission
hematologic malignancy
cell transplantation
  • 1 views
  • 25 Jan, 2021
  • 1 location
None
Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

standard-of-care for prescription of some targeted therapies in non-small cell lung cancer (blood-based T790M companion diagnostic test). cfDNA can be detected not only in plasma but also in urine, even in

intravesical bcg
bladder tumor
bladder carcinoma
gilbert's syndrome
neutrophil count
  • 0 views
  • 19 Aug, 2021
  • 1 location