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Found 597 clinical trials
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Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)

This is a study for participants with a type of blood cancer called mantle cell lymphoma (MCL). The main purpose is to compare LOXO-305 to other drugs that work in a similar way that have

cancer
ibrutinib
acalabrutinib
neutrophil count
btk inhibitor
  • 11 views
  • 18 Nov, 2021
  • 130 locations
None
Azole-echinocandin Combination Therapy for Invasive Aspergillosis

The goals of this study are 3-fold: First, the main study and the primary endpoint will evaluate if the overall mortality can be decreased with initial azole-echinocandin combination therapy compared with triazole monotherapy in patients with IA and documented voriconazole susceptibility. Second, the study design described will also allow to …

  • 0 views
  • 16 Oct, 2021
  • 4 locations
None
A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

hematological malignancies that harbor IDH mutations.

  • 2 views
  • 26 Apr, 2021
  • 3 locations
None
Busulfan and Fludarabine as Conditioning for Allogeneic Stem Cell Transplantation: a Pharmacokinetic Study

A study of pharmacokinetics of daily intravenous busulfan

fludarabine
cell transplantation
busulfan
  • 38 views
  • 07 Nov, 2020
  • 1 location
None
Extracorporal Photopheresis Pilot Study

ECP will be given to the patients [UVAR®XTS TM Therakos system, Johnson & Johnson] according to the following schedule: Starting at day 21 after transplant, if hematologic recovery allowed it: 2 ECP per week the first 2 weeks, and 1 ECP per week during 1 month. Total = 8 ECP …

cancer
allogeneic transplantation
myeloablative conditioning
  • 16 views
  • 07 Nov, 2020
  • 1 location
None
Allogeneic Hematopoietic Stem Cell Transplantation

To assess the engraftment of hematopoietic stem cells following reduced-intensity conditioning in children presenting with solid tumors or hematological malignancy by evaluating post

cell transplantation
allogeneic transplantation
thymoglobulin
fludarabine
hla-a
  • 18 views
  • 07 Nov, 2020
  • 1 location
None
Intrabone Cord Blood Transplantation

The purpose of this study is to evaluate the viability of intrabone administration of umbilical cord blood as allogenic transplantation for the treatment of hematologic malignancies.

cancer
umbilical cord blood transplantation
  • 20 views
  • 07 Nov, 2020
  • 1 location
None
  • 0 views
  • 15 Feb, 2021
  • 1 location
None
Evolution of Thromboelastography During Tranexamic Acid Treatment

Patients with hematological malignancies are at increased risk of bleeding, especially during intensive chemotherapy. The aim of this study is to compare by thromboelastography changes during

  • 0 views
  • 28 Jan, 2021
  • 2 locations
None
PET/CT Guided Antifungal Stewardship in Invasive Pulmonary Aspergillosis

OPTIFIL is a pilot prospective multicenter study based over the hypothesis that the normalization of the functional imaging 18F-FDG-PET/CT during the Invasive pulmonary aspergillosis (IPA) could occur earlier than that of conventional imaging. This study evaluates the therapeutic response through a systematic 18F-FDG-PET/CT at week 6. The latter response will …

  • 31 views
  • 27 Jan, 2021
  • 1 location