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Found 2121 clinical trials
Featured trial
INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

This Phase 1/2, open-label, dose-finding study is intended to evaluate the safety and tolerability, PK, PD, and efficacy of INCB000928 administered as monotherapy or in combination with ruxolitinib in participants with MF who are transfusion-dependent or presenting with symptomatic anemia. This study will consist of 2 parts: dose escalation and …

  • 0 views
  • 25 May, 2022
  • 16 locations
Featured trial
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

Background: Stem cell transplants from related donors (allogenic stem cell transplants) can be used to treat individuals with certain kinds of severe blood diseases

myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
anemia studies
anemia
  • 190 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the

myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
anemia studies
anemia
  • 172 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Advanced Stage Non-small Cell Lung Cancer

Advanced Stage Non-small Cell Lung Cancer

  • 258 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase 2, 12-week, double-blind, randomized, parallel group, placebo-controlled study of four doses of Study Medication in subjects with moderate to severe rheumatoid arthritis

A Phase 2, 12-week, double-blind, randomized, parallel group, placebo-controlled study of four doses of Study Medication in subjects with moderate to severe rheumatoid arthritis

  • 290 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Do you suffer from Hemorrhoids?

Do you suffer from Hemorrhoids?

  • 1549 views
  • 25 Mar, 2021
  • 1 location
Sequential Conditioning in Haploidentical Transplantation for Hematopoietic Stem Cells in Patients With Relapsed or Refractory Lymphoid Hematological Disorders

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment option with a significant chance of healing in lymphoid hematological refractory or multiple relapses after chemotherapy. However, all patients with an indication of allo-HSC can not benefit because of two limitations: the toxicity of the treatment and graft shortage available. …

  • 6 views
  • 24 Jan, 2021
  • 2 locations
Anti-CD33 CAR NK Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia

CAR technology has been used in T cell therapy and gets great success in treating hematological diseases. Following models of CAR T cells, CAR NK cell therapy has been one hot point. For myeloid

hematologic disorder
cell transplantation
remission
flow cytometry
fludarabine
  • 0 views
  • 25 Mar, 2022
  • 1 location
A Monoclonal Antibody Conditioning Regimen for Allogeneic Stem Cell Transplant in Patients With Fanconi Anemia.

Patients eligible for this study have an aggressive blood disease, Fanconi Anemia (FA) that requires an allogeneic (meaning the cells come from a donor) stem cell transplant using a

fludarabine
anemia
campath
graft versus host disease
  • 44 views
  • 07 Nov, 2020
  • 1 location
Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

Background Severe aplastic anemia (SAA) is a rare and serious blood disorder. It causes the immune system to turn against bone marrow cells. Standard treatment for

aplastic anemia
neutrophil count
blood disorder
antithymocyte globulin
horse anti-thymocyte globulin
  • 12 views
  • 28 May, 2022
  • 1 location