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Found 42 clinical trials
CBT4CBT With Spanish Alcohol Users

Specific aims are as follows: To adapt our existing CBT4CBT program for use with Spanish-speaking alcohol users in a web-based platform To conduct an 8-week randomized trial evaluating the feasibility and efficacy of adding CBT4CBT-Spanish to treatment as usual in a community based treatment program in a population of 90 …

  • 0 views
  • 14 Mar, 2022
  • 5 locations
Game Plan for PrEP

This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their alcohol use, and improve key outcomes of PrEP care, including adherence, persistence, and STI rates. Men with a history of …

  • 0 views
  • 10 Sep, 2021
  • 1 location
The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study

A phase II randomized, double-blind, placebo-controlled clinical trial (RCT) to evaluate the ability of zonisamide (ZON) to decrease alcohol use among treatment-seeking adults with an alcohol use disorder (AUD).

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
CBT-I on Alcohol Treatment Outcomes Among Veterans (Project SAVE)

Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.

insomnia
cognitive therapy
cognitive behavioral therapy for insomnia
behavior therapy
Accepts healthy volunteers
  • 25 views
  • 15 Feb, 2022
  • 1 location
ED Initiated Oral Naltrexone for AUD

This study will recruit Emergency Department (ED) patients with moderate to severe alcohol use disorder (AUD) who are interested in initiating medication assisted treatment (MAT). The study is split into two phases. The first phase (N=10) will use implementation science strategies to strengthen existing non-targeted ED based AUD screening program …

  • 0 views
  • 24 Mar, 2022
  • 1 location
Using CBPR to Engage Hazardous Drinking Women in the HIV Prevention and Care Continuum

Unhealthy alcohol use among women with and at risk for HIV can interrupt critical steps in the HIV prevention and care continuum, is associated with HIV transmission risk behaviors, and contributes to health disparities. Thus it is critical to accurately identify alcohol use and implement alcohol interventions among women with …

HIV Vaccine
  • 0 views
  • 07 Oct, 2021
  • 1 location
Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

Background Drugs like nalmefene interfere with opioid receptors. This might reduce drinking. The gene OPRM1 determines opioid receptor functions. Researchers want to see if nalmefene affects people s responses to alcohol cues. They also want to compare how nalmefene affects people with different forms of OPRM1. Objectives To test nalmefene …

Accepts healthy volunteers
  • 9 views
  • 09 May, 2022
  • 1 location
Pioglitazone for the Treatment of Alcohol Use Disorder (PAUSE)

Alcohol Use Disorder (AUD) is common among Veterans but medication treatment is used infrequently and the impact of these treatments are small to moderate at best. Pioglitazone, a medication FDA approved for diabetes, has been shown in pre-clinical studies to reduce alcohol. The proposed study will test the efficacy of …

antidepressants
diabetes
heavy drinking
scid
  • 29 views
  • 01 May, 2022
  • 2 locations
Mobile Mindfulness for Alcohol Use and PTSD Among Veterans

The purpose of the present study is to develop and test a mobile mindfulness intervention for Alcohol Use Disorder and PTSD among OEF/OIF veterans

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence

Suvorexant (trade name Belsomra) is an orexin receptor antagonist that has TGA approval for the treatment of insomnia, characterised by difficulties with sleep onset and/or sleep maintenance. It may also have a role in addictions as the orexins play a critical role in drug addiction and reward-related behaviours. Orexins appear …

suvorexant
sleep disorder
  • 0 views
  • 27 Aug, 2021
  • 1 location