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Found 35 clinical trials
Nurse-led Alcohol Brief Intervention Plus Mobile Personalized Chat-based Support on Reducing Alcohol Use in University Students

This study aims to assess the effect of personalized support using instant messaging application on alcohol drinking reduction in university students proactively recruited from universities in Hong Kong.

  • 23 Sep, 2021
  • 1 location
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling

The main purpose of this study is to see whether heavy drinking will interfere with a specific pathway, called FXR signaling in the liver. The abnormality of this pathway may lead to liver

  • 22 Sep, 2021
  • 1 location
CBT-I Augmentation of TOP for Sobriety and Insomnia in AUD

promise in improving abstinence and decreasing heavy drinking but without any clinical improvement in sleep continuity. The recommended treatment for insomnia is Cognitive Behavioral Therapy for Insomnia

  • 19 Aug, 2021
  • 2 locations
Surgical Weight Loss and Alcohol Perception

. Heightened reactivity (e.g., attention bias; craving) to alcohol-related cues is known to signify increased risk for heavy drinking and AUD. No research to date has examined whether the increased sensitivity

bypass surgery
gastric bypass
Accepts healthy volunteers
  • 18 Nov, 2021
  • 1 location
Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture

Gut microbiota regulate metabolism of their human host. Some diseases are associated with variations in gut microbiota diversity and higher fracture risk. Intestinal bacteria synthesize or influence synthesis of factors modulating bone metabolism. The link between gut microbiota and bone was assessed mainly in experimental animal studies. Clinical data, e.g. …

postmenopausal osteoporosis
spinal fracture
bone densitometry
quantitative computed tomography
bone mineral density
  • 23 Jan, 2021
  • 1 location
Using Telehealth to Address Alcohol Misuse in HIV Care

This project will test the effects of a telehealth counseling program on reducing alcohol use and improving HIV viral control among people with HIV who drink heavily. In total, 600 heavy drinkers with HIV will be assigned to either (a) a single session of brief counseling on alcohol use or …

  • 30 Jul, 2021
  • 1 location
Mobile Health for Alcohol Use Disorders in Clinical Practice

This study evaluates the impact on risky drinking days and quality of life for patients with alcohol use disorder among patients who use a mobile health smart phone application. A third of the participants will receive access to the smart phone app without any monitoring; a third of the participants …

  • 27 Sep, 2021
  • 1 location
Using Counter Attitudinal Advocacy to Change Drinking Behavior

High volume drinking by young adults has proven resistant to change, so new approaches are needed. We adapt a theory-based attitude change strategy for use in alcohol prevention. This research tests the impact of brief writing and advocacy activities on subsequent drinking and negative consequences.

  • 22 May, 2021
  • 2 locations
Drinkers' Intervention to Prevent Tuberculosis (DIPT Study)

There is an urgent global need to decrease the high mortality of tuberculosis (TB) in persons with HIV as TB is the leading cause of death among persons with HIV worldwide. The DIPT (Drinkers' Intervention to Prevent TB) study is a randomized, 2x2 factorial trial among HIV/TB co-infected adults in …

heavy drinking
skin test
  • 11 Jul, 2021
  • 2 locations
Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy

The purpose of this study is to evaluate the safety and efficacy of dutasteride in reducing drinking and heavy drinking in men and women with alcohol use disorder. The investigators hypothesize

heavy drinking
  • 28 Jul, 2021
  • 1 location