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Found 351 clinical trials
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients (PANDORA)

detrimental complications of cardiac surgery in older adults.

bypass graft
heart surgery
postoperative delirium
coronary artery bypass graft
  • 3 views
  • 12 Sep, 2023
  • 7 locations
The eFfect of cOntinuous Low Tidal Volume Ventilation With Hyperoxia Avoidance During CardiopUlmonary Bypass "FOCUS" Trial

This is a multi-institutional study (CCF, UPMC, OSU) evaluating different ventilation strategies during cardiopulmonary bypass on mortality and postoperative pulmonary complications.

cardiopulmonary bypass
  • 0 views
  • 27 Oct, 2022
  • 1 location
Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation (NOVACC)

following cardiac surgery decreases the number of patients with acute renal failure and/or death compared with the usual use of norepinephrine. Participation in the study involves daily follow-up at

  • 0 views
  • 20 Sep, 2023
  • 1 location
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart preservation (NIHP) in a randomized clinical multicentre trial. The primary hypothesis is that the non-ischemic hypothermic cardioplegic preservation (NIHP) is safe and superior to ischemic cold static storage (ICSS) …

lupus
organ transplantation
heart transplantation
heart disease
heart transplant
  • 0 views
  • 04 Oct, 2022
  • 12 locations
Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery (ASSURE-DES)

The purpose of this study is to evaluate the safety and effectiveness of perioperative antiplatelet therapy in patients with drug-eluting stent undergoing non-cardiac surgery.

  • 7 views
  • 24 Feb, 2022
  • 23 locations
ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE (ARTEMIS)

in adult participants with CKD who undergo non-emergent cardiac surgery with CPB.

  • 0 views
  • 20 Sep, 2023
  • 48 locations
CHIlled Platelet Study "CHIPS" (CHIPS)

A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room

  • 0 views
  • 20 Sep, 2023
  • 22 locations
Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function: The PROTECT IV Trial (PROTECT IV)

symptoms, heart function and health after a heart procedure compared to the current standard of care.

infarct
bypass graft
clot
ischemia
in stent restenosis
  • 0 views
  • 11 Oct, 2022
  • 54 locations
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial (LeAAPS)

(LAAE) for the prevention of ischemic stroke or systemic arterial embolism in subjects undergoing cardiac surgery who have risk factors for atrial fibrillation and ischemic stroke.

Accepts healthy volunteers
  • 0 views
  • 13 Aug, 2023
  • 27 locations
Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter (TIGHT-K)

of new onset atrial fibrillation after cardiac surgery (AFACS) in patients undergoing isolated coronary artery bypass graft (CABG) surgery.

fibrillation
  • 0 views
  • 22 Apr, 2022
  • 1 location