Found 577 clinical trials
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Accepting pediatric ages
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Accepting Seniors
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1000s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures.
The main objection is to investigate molecular biology of myocardial damage during cardiac surgery procedures.
- 0 views
- 24 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Patient Blood Management in Cardiac Surgery
Preoperative anemia is associated with an important increase in transfusions of red blood cells (RBC) compared to a non-anemic patient in cardiac and non cardiac surgery. Furthermore transfusion
- 0 views
- 23 Jan, 2021
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Dexamethasone for Cardiac Surgery-II Trial
Background. Numerous studies have investigated high-dose corticosteroids in cardiac surgery, but with mixed results leading to ongoing variations in practice around the world. The Dexamethasone
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Ischaemic PReconditioning In Non Cardiac surgEry
Several randomized trials suggested a cardioprotective beneficial effect (eg reduction in cardiac troponin release) of remote ischemic preconditioning in cardiac surgery. Remote ischemic
- 19 views
- 26 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Prevention of Infections in Cardiac Surgery
There is clinical equipoise about the question of whether antibiotic prophylaxis should be given for a short period or an extended period of time as reflected by inconsistencies in major guidelines, current practices at Canadian centers, and as concluded in the three systematic reviews. There also is clinical equipoise on …
- 15 views
- 25 Jan, 2021
- 4 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery.
nephro-protective effects are preserved in critical illness. Cardiac surgery appears to be the best setting to test the likely beneficial renal effects of amino acid because of pathophysiological
- 1 views
- 29 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Prophylactic Use of Milrinone After Congenital Heart Surgery in Infants
This randomized, multi-center, double-blinded, placebo-controlled study is designed to evaluate the efficacy and safety of milrinone compared with placebo in participants after corrective surgery for congenital heart disease. Participants will be randomized in a 1:1 ratio within 90 minutes after arriving in the intensive care unit (ICU), to receive either …
- 0 views
- 22 Jan, 2021
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Spironolactone and Perioperative Atrial Fibrillation Occurrence in Cardiac Surgery Patients.
Study hypothesis : Pre-operative aldosterone receptor blockade may reduce post-operative atrial fibrillation (POAF) occurrence within 5 days after coronary artery bypass graft surgery (CABG) aortic valve replacement (AVR) without any heart failure or any mitral surgery. Primary efficacy criterion : occurrence of POAF occurring from randomization and within 5 days …
- 15 views
- 22 Jan, 2021
- 2 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery
elderly after cardiac surgery and is associated with worse outcomes. Causes leading to delirium are multifactorial but sleep disturbances remains an important one. In previous studies, sedative-dose
- 6 views
- 26 Jan, 2021
- 2 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Cardiology/Vascular Diseases
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Currently Recruiting
Outcome Impact of Different Tranexamic Acid Regimen in Cardiac Surgery With Cardiopulmonary Bypass
strategies and technologies that limit patient exposure to this risk. The single largest consumer of this resource continues to be cardiac surgery, with 20% of the world wide use of allogeneic blood products
- 0 views
- 25 Jan, 2021
- 1 location