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Found 577 clinical trials
Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures.

The main objection is to investigate molecular biology of myocardial damage during cardiac surgery procedures.

heart disease
bypass graft
heart surgery
  • 0 views
  • 24 Jan, 2021
  • 1 location
Patient Blood Management in Cardiac Surgery

Preoperative anemia is associated with an important increase in transfusions of red blood cells (RBC) compared to a non-anemic patient in cardiac and non cardiac surgery. Furthermore transfusion

taco
blood transfusion
heart surgery
  • 0 views
  • 23 Jan, 2021
  • 1 location
Dexamethasone for Cardiac Surgery-II Trial

Background. Numerous studies have investigated high-dose corticosteroids in cardiac surgery, but with mixed results leading to ongoing variations in practice around the world. The Dexamethasone

corticosteroids
  • 0 views
  • 26 Jan, 2021
  • 1 location
Ischaemic PReconditioning In Non Cardiac surgEry

Several randomized trials suggested a cardioprotective beneficial effect (eg reduction in cardiac troponin release) of remote ischemic preconditioning in cardiac surgery. Remote ischemic

propofol
troponin
coronary disease
cardiovascular complications
cardiac troponin
  • 19 views
  • 26 Jan, 2021
  • 1 location
Prevention of Infections in Cardiac Surgery

There is clinical equipoise about the question of whether antibiotic prophylaxis should be given for a short period or an extended period of time as reflected by inconsistencies in major guidelines, current practices at Canadian centers, and as concluded in the three systematic reviews. There also is clinical equipoise on …

vancomycin
equipoise
cefazolin
heart surgery
  • 15 views
  • 25 Jan, 2021
  • 4 locations
Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery.

nephro-protective effects are preserved in critical illness. Cardiac surgery appears to be the best setting to test the likely beneficial renal effects of amino acid because of pathophysiological

acute renal failure
continuous infusion
crystalloid solutions
critical illness
hypoperfusion
  • 1 views
  • 29 Jan, 2021
  • 1 location
Prophylactic Use of Milrinone After Congenital Heart Surgery in Infants

This randomized, multi-center, double-blinded, placebo-controlled study is designed to evaluate the efficacy and safety of milrinone compared with placebo in participants after corrective surgery for congenital heart disease. Participants will be randomized in a 1:1 ratio within 90 minutes after arriving in the intensive care unit (ICU), to receive either …

  • 0 views
  • 22 Jan, 2021
Spironolactone and Perioperative Atrial Fibrillation Occurrence in Cardiac Surgery Patients.

Study hypothesis : Pre-operative aldosterone receptor blockade may reduce post-operative atrial fibrillation (POAF) occurrence within 5 days after coronary artery bypass graft surgery (CABG) aortic valve replacement (AVR) without any heart failure or any mitral surgery. Primary efficacy criterion : occurrence of POAF occurring from randomization and within 5 days …

electrocardiogram
heart failure
coronary artery bypass graft
electrocardiographic monitoring
bypass graft
  • 15 views
  • 22 Jan, 2021
  • 2 locations
Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery

elderly after cardiac surgery and is associated with worse outcomes. Causes leading to delirium are multifactorial but sleep disturbances remains an important one. In previous studies, sedative-dose

postoperative delirium
propofol
sedative
cerebral dysfunction
mechanical ventilation
  • 6 views
  • 26 Jan, 2021
  • 2 locations
Outcome Impact of Different Tranexamic Acid Regimen in Cardiac Surgery With Cardiopulmonary Bypass

strategies and technologies that limit patient exposure to this risk. The single largest consumer of this resource continues to be cardiac surgery, with 20% of the world wide use of allogeneic blood products

postoperative bleeding
blood transfusion
tranexamic acid
pump prime
cardiopulmonary bypass
  • 0 views
  • 25 Jan, 2021
  • 1 location