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Found 351 clinical trials
Tocilizumab, Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac Surgery (GLORIOUS-II)

Open heart surgery, including coronary artery bypass grafting (CABG) and/or aortic valve replacement (AVR) is associated with a significant risk of mortality. This study is a randomized

  • 06 Apr, 2023
Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery. (PROTection)

nephro-protective effects are preserved in critical illness. Cardiac surgery appears to be the best setting to test the likely beneficial renal effects of amino acid because of pathophysiological

acute renal failure
continuous infusion
critical illness
kidney injury
  • 12 Jul, 2022
  • 16 locations
The Direct Oral Anticoagulation Versus Warfarin After Cardiac Surgery Trial

cardiac surgery in patients with an indication for oral anticoagulation.

  • 21 Aug, 2021
  • 1 location
Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial) (PACO)

from a physiotherapist specialized to cardiac operation patients. These videos are available on the ExSed application during the intervention. The physiotherapist will also contact each patient (by

rehabilitation program
bypass graft
heart surgery
aortic valve replacement
  • 02 Mar, 2022
  • 1 location
Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial) (COIN)

18 years or older and undergo elective non-cardiac surgery with general anesthsia will be enrolled. The intervention is intravenous infusion of colloids or crytalloids before induction of general

  • 26 Aug, 2023
  • 1 location
Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery (ALPHA2PREVENT)

for the prevention of delirium and cognitive decline in male and female participants aged 70+ scheduled for open heart surgery.

  • 07 Oct, 2022
  • 4 locations
Pre-operative Carriage of Respiratory VIRUSes, and Acute Respiratory Distress Syndrome After Heart Surgery (VIRUS-ATTAC)

) after cardiac surgery. Cardiac surgery patients are particularly at risk of developing ARDS with an estimated incidence of 5-10% based on the most recent data.

  • 10 May, 2022
  • 4 locations
Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula

The purpose of this study is to compare reintubation rates and outcomes of patients treated with high-flow nasal canula oxygen therapy (HFNC) and patients treated with provider choice of standard care.

  • 03 Apr, 2023
  • 1 location
Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients

This topic will focus on the following questions: Part one: To clarify the relationship between preoperative frailty and myocardial injury (cTnT ≥0.03) after non-cardiac surgery in

  • 12 Apr, 2023
  • 1 location
A Clinical Trial of the Use of Remote Heart Rhythm Monitoring With a Smartphone After Cardiac Surgery (SURGICAL-AF 2)

The objective of the study is to evaluate the clinical consequences following the detection of postoperative atrial fibrillation or flutter (POAF) using a remote heart rhythm monitoring strategy with a photoplethysmography based smartphone technology in the early postoperative period after discharge.

coronary artery bypass graft
diagnostic procedure
  • 04 Oct, 2022
  • 1 location