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Found 88 clinical trials
Featured trial
B3461087 - Tafamidis

heart failure with preserved ejection fraction (HFpEF)].

  • 0 views
  • 09 Jun, 2022
  • 5 locations
Featured trial
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved Ejection Fraction (HFpEF)

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved

  • 1014 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A Randomized Parallel-group, Placebo-controlled, Double-blind, Multi-center Dose Finding Phase II Trial Exploring the Pharmacodynamic Effects, Safety and Tolerability, and Pharmacokinetics of Four Dose Regimens of the Oral sGC Stimulator BAY1021189 Over 12 Weeks in Patients With Worsening Heart Failure and Preserved Ejection Fraction (HFpEF) SOCRATES-PRESERVED

A Randomized Parallel-group, Placebo-controlled, Double-blind, Multi-center Dose Finding Phase II Trial Exploring the Pharmacodynamic Effects, Safety and Tolerability, and Pharmacokinetics of Four Dose Regimens of the Oral sGC Stimulator BAY1021189 Over 12 Weeks in Patients With Worsening Heart Failure and Preserved Ejection Fraction (HFpEF) SOCRATES-PRESERVED

  • 530 views
  • 08 Nov, 2020
  • 1 location
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction (SPIRRIT)

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With

natriuretic peptide
aldosterone
nt-probnp
n-terminal pro-bnp
aldosterone antagonists
  • 69 views
  • 04 Oct, 2022
  • 67 locations
"HerzCheck" - Detection of Early Heart Failure Using Telemedicine in Structurally Weak Regions

This study is intended to provide a basis for decision-making for the improved medical care of patients with asymptomatic heart failure, especially in structurally weak regions.

  • 0 views
  • 08 Dec, 2021
  • 1 location
Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40% (ENDEAVOR)

This is a randomised, double-blind, placebo-controlled, multi-center sequential phase 2b and Phase 3 study to evaluate the efficacy and safety of AZD4831 administered for up to 48 Weeks in participants with heart failure with left ventricular ejection fraction > 40%. The study will consist of 2 separate parts, Part A …

  • 2 views
  • 07 Oct, 2022
  • 119 locations
Acute Heart Failure With Preserved Ejection Fraction - COngestion Discharge Evaluation

The AHF-CODE preserved study is a prospective, non-randomized, monocenter study performed in patients with heart failure with preserved ejection fraction admitted for worsening heart failure

  • 12 views
  • 02 Feb, 2021
  • 1 location
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction

The global objective of this study is to determine the mechanisms of exercise intolerance and dyspnea on exertion (DOE) in patients with HFpEF and based on this pathophysiology, test whether specific exercise training programs (whole body vs single leg) will result in improved exercise tolerance.

diastolic dysfunction
ejection fraction
dyspnea
heart failure with preserved ejection fraction
  • 0 views
  • 27 May, 2022
  • 1 location
Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction Pilot Study (Met-PEFpilot)

diversity, leaky gut, and systemic inflammation in patients with 80 older patients with heart failure with preserved ejection fraction (HFpEF).

  • 0 views
  • 23 Oct, 2022
  • 1 location
Physiologic Accelerated Pacing as a Treatment in Patients With Heart Failure With Preserved Ejection Fraction (PACE HFpEF)

Part I: Week 0-12: Quantify the effects of lower heart rate (HR) elevation on symptoms and function in patients with heart failure with preserved ejection fraction (HFpEF). The

  • 0 views
  • 04 Oct, 2022
  • 1 location