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Found 218 clinical trials
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A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy

A Phase 3 multi-institutional study for treatment of children with newly diagnosed hepatoblastoma using a modified Paediatric Hepatic International Tumour Trial (PHITT) strategy incorporating a randomized assessment of sodium thiosulfate as auditory protection for children with localized disease, and response adapted therapy for patients with metastatic disease

cancer therapy
fluorouracil
vincristine
cancer
glomerular filtration rate
  • 0 views
  • 27 Mar, 2021
  • 1 location
None
Safety and Efficacy of Etravirine in Friedreich Ataxia Patients

A drug repositioning effort provided evidence supporting the possible use of Etravirine, a drug approved for the treatment of HIV infections in patients starting from 2 years of age, as a treatment for FA. We found that Etravirine is able to increase Frataxin protein both in vitro - in cells …

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
Transcranial Magnetic Stimulation (TMS) in Schizophrenia

Until recently stimulation of nervous tissue deeper than approximately 2 cm from the scalp (will hence be called non-deep TMS) was not possible (3).A new coil ("H"-coil invented in Weizmann Institute of Science, Neurobiology Department, Rehovot, Israel ) capable of stimulating more than twice this depth (Up to 5 cm)was …

psychotropic drugs
suicide
auditory hallucinations
hallucinations
  • 8 views
  • 07 Nov, 2020
  • 1 location
None
Pitch Perception and Memory: Deficits and Training

perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both compared with control listeners. Behavioral, EEG, and MEG measures are collected in

  • 47 views
  • 02 Feb, 2021
  • 1 location
None
The KHENEREXT Study

This is an open-label, multi-centre study in subjects with a genetically confirmed mitochondrial deoxyribonucleic acid (DNA) transfer ribonucleic acid (tRNA)Leu(UUR) m.3243A>G mutation who completed study KH176-202. In the KH176-203 study subjects will be receiving KH176 100 mg BID or KH176 50 mg bid in die (BID) (as determined by the …

  • 0 views
  • 03 Nov, 2021
  • 4 locations
None
  • 0 views
  • 12 Aug, 2021
  • 6 locations
None
Maternal B12 Supplementation to Improve Infant B12 Deficiency and Neurodevelopment

Vitamin B12 plays a key role in the development and normal functioning of the brain and nervous system. Unborn and new-born infants derive their vitamin B12 stores almost entirely from maternal B12 stores. As such, infants who are born to vegetarian mothers and exclusively breast fed are at a high-risk …

vitamins
malnutrition
vitamin b12
vitamin b12 supplementation
  • 12 views
  • 22 Jan, 2021
  • 2 locations
None
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …

beta human chorionic gonadotropin
primary tumor
cancer
etoposide
testicular
  • 349 views
  • 27 Oct, 2021
  • 374 locations
None
Prevention of Epilepsy by Reducing Neonatal Encephalopathy

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

electroencephalogram
  • 0 views
  • 25 Jan, 2021
  • 3 locations
None
Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial

asymmetric hearing loss (AHL) or single-sided deafness (SSD). Post-implant performance with a CI alone is expected to outperform pre-implant performance with a HA. The study also evaluates the effectiveness

hearing screening
cochlear implant
Accepts healthy volunteers
hard of hearing
audiogram
  • 0 views
  • 02 Nov, 2021
  • 5 locations