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Found 331 clinical trials
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus (MERMAID-T1D)

In type 1 diabetes (T1DM), automated insulin delivery (AID) systems such as the hybrid closed loop artificial pancreas (HCL AP) combine the use of an insulin pump, continuous blood sugar monitor, and control algorithm to adjust background insulin delivery to improve time in target blood sugar range. Systems such as …

diabetes
c-peptide
type 2 diabetes mellitus
insulin
type 1 diabetes mellitus
  • 0 views
  • 04 Oct, 2022
  • 1 location
MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.

Research hypothesis: pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism Elevated CRP and homocysteine values are associated with poorer perinatal outcome. reduced concentrations of folic acid and vitamin B 12 are associated with higher homocitein values Carriers of …

diabetes
folic acid
  • 0 views
  • 21 Dec, 2021
  • 2 locations
CUlturally Sensitive TOols for Ethnic Minorities in Diabetes Self-management Education and Support (CUSTOM)

The CUSTOM research project represents a complex intervention. The project aim of the intervention is, through the delivery of culturally sensitive Diabetes self-management education and support, to support ethnic minorities with type 2 diabetes in making health-promoting decisions about their care and gaining insight into their goals, values and motivation …

  • 1 views
  • 07 Feb, 2022
  • 1 location
the Efficacy of Fetal Arterial and Venous Doppler Indices in Predicting Perinatal Outcome

To determine and evaluate the diagnostic performance of Doppler sonography of umbilical artery (UA), fetal middle cereberal artery (MCA), ductus venosus (VD) and umbilical vein (UV) for prediction of adverse perinatal outcome among diabetic pregnant women.

hemoglobin a1c
sugars
prenatal
fasting
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabetes (SAMBA)

This project will assess the independent predictors of impaired muscle and bone strength through a longitudinal observation of a cohort of subjects with type 1 and 2 diabetes consecutively attending an outpatients diabetes clinics for the annual screening of complications.

diabetes
  • 21 views
  • 24 Feb, 2022
  • 1 location
Glycaemic Variability in Acute Stroke (G-VAS)

Increased glycaemic variability is associated with worse outcome in patients with diabetes after acute stroke.

diabetes
acute stroke
hemoglobin a1c
glycosylated hemoglobin
ischemic stroke
  • 32 views
  • 04 Oct, 2022
  • 1 location
BEAM: Brain-Eye Amyloid Memory Study (BEAM)

The main objectives for this study are: To investigate novel, non-invasive ocular measurements including optical coherence tomography and eye tracking in a cross-sectional study of participants with various neurodegenerative dementias against standard cognitive assessments and brain imaging measures; and To assess the potential utility of ocular assessments for early detection …

optical coherence tomography
amyloid
parkinson's disease
cognitive assessment
alzheimer's disease
  • 32 views
  • 25 Jan, 2022
  • 5 locations
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly (SmartAge)

Cognitive disorders increase with age and in the presence of metabolic diseases such as Type 2 Diabetes Mellitus (T2DM). In addition, digestive disorders, changes in dietary pattern and decreased activity negatively influence the microbiome. The hypothesis is that pharmacological intervention with metformin will modify the composition of the gut microbiota …

metformin
type 2 diabetes mellitus
continuous glucose monitoring
  • 0 views
  • 04 Oct, 2022
  • 1 location
Inter-relationships Among Glucose, Brain, Gut Microbiota and MicroRNAs (IRONmiRNA). (IRONmiRNA)

The brain is a recognized target of iron deposition. This process is enhanced by the presence of obesity and hyperglycemia and impacts cognitive functions. There is evidence suggesting that the gut microbiota composition modulates this process. It has been proposed that microRNAs are mediators in the dialogue between the composition …

bariatric surgery
Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location
Effects of Cross-sex Hormone Therapy on Eating Behavior Metabolism Energy Balance and Cardiovascular System

Current study aims to characterize five highly interconnected physiological systems in patients undergoing cross-sex hormone therapy - namely glucose and lipid metabolism, energy balance, eating behavior, functional brain networks involved in the regulation of eating behavior and the cardiovascular system - to gain novel insights into the effects of sex …

insulin resistance
Accepts healthy volunteers
insulin
  • 1 views
  • 04 Oct, 2021