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Found 194 clinical trials
PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn

The purpose of this study is to determine if normally occurring variations in a specific gene called PTGS-1 are associated with an increased risk of narrowing of the ductus arteriosus from exposure to over-the-counter pain medicines (NSAIDs).

  • 24 Jan, 2021
  • 1 location
Natural History Study of ATP1A3-related Disease

An observational study aiming to study the natural history of a UK-wide patient cohort with ATP1A3-related disease.

  • 18 Feb, 2021
  • 1 location
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment Biomarker Identification Development of Novel Phenotyping Measures and Discovery of Therapeutic Targets

Background Disorders of hearing instability (HI) are poorly characterized and ineffectively treated. HI can cause fluctuations in hearing thresholds and speech understanding. Researchers want to use a specialized form of magnetic resonance imaging (MRI) and blood tests to learn more about HI. Objective To characterize a cohort of people with …

  • 16 Apr, 2021
  • 1 location
Perinatal Stroke: Understanding Brain Reorganization

The incidence of perinatal stroke is relatively common, as high as 1 in 2,300 births, but little is known about the resulting changes in the brain that eventually manifest as cerebral palsy (CP). More importantly, no therapy has been devised to mitigate these specific maladaptive changes leading to hemiplegic CP. …

transcranial magnetic stimulation
cerebral palsy
  • 09 Apr, 2021
  • 1 location