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Found 191 clinical trials
Natural History Study of Usher Syndrome ( Light4Deaf )

, which will be valuable for the foreseen USH clinical trials. The clinical arm of the project aims at performing a deep-phenotyping of retinal degeneration, hearing loss, vestibular dysfunction

  • 0 views
  • 27 Jan, 2021
  • 4 locations
Natural History Study - Mitochondrial Disease

Carriers of the m.3242A>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal issues, and many other symptoms

  • 21 views
  • 24 Jan, 2021
  • 1 location
Bone Conduction Implant and MRI

Bone conduction implants (BCI) are widely used in cases of conductive/ mixed hearing loss or single side deafness when surgical treatment or air hearing aids are not feasible. There are two

  • 0 views
  • 26 Jan, 2021
  • 1 location
Genotype-phenotype Correlation Study of Presymptomatic and Symptomatic DFNA9 Patients

DFNA9 (Deafness Autosomal Dominant 9) is an autosomal dominant hereditary hearing loss which is associated with vestibular deterioration. The most recent genotype-phenotype correlation studies

dfna9
deafness
hereditary hearing loss
  • 0 views
  • 24 Jan, 2021
  • 1 location
Prediction of Brain Injury in Premature Infants

associated with neurodevelopmental delay, poor cognitive performance, visual and hearing impairment, epilepsy, and cerebral palsy; and instability of systemic hemodynamics during transition from intra- to

hearing impairment
periventricular leukomalacia
premature birth
prematurity
closed head injuries
  • 10 views
  • 24 Jan, 2021
  • 3 locations
Natural History Study of Patients With Neurofibromatosis Type 2

identify imaging biomarkers of hearing loss in NF2. We will attempt to discover the mode of peripheral neuropathy in patients with NF2. Lastly, we will attempt to discover previously unknown

genetic testing
neurofibromatosis type ii
spinal cord
blood tests
MRI Scan
  • 18 views
  • 28 Feb, 2021
  • 1 location
Effects of Transitional Circulation in ELBW Infants

their intestines. Some long term effects include hearing loss, developmental delay, and learning problems in the future that are worse than other premature babies who did not have hypotension

prematurity
electrocardiogram
extremely low birth weight
hypotensive
blood test
  • 20 views
  • 26 Jan, 2021
  • 2 locations
Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention

The purpose of this research study is to develop and evaluate a parent training program, which aims to improve language. The study is being conducted to see if teaching parents positive parenting techniques and behavior strategies will improve the rate of language development in children with cochlear implants when compared …

speech therapy
hard of hearing
cochlear implant
audiogram
  • 14 views
  • 26 Jan, 2021
  • 1 location
Mitochondrial Genetics of Presbycusis

The main goal of this study is to identify mitochondrial mutations associated with presbycusis. Patients affected by severe presbycusis and normal hearing controls (according to ISO7029 norm) will be enrolled if satisfying inclusion criteria (aged from 40 to 80 years old) in existing biocollections in the University Hospital of Angers. …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Natural History Study of ATP1A3-related Disease

An observational study aiming to study the natural history of a UK-wide patient cohort with ATP1A3-related disease.

  • 0 views
  • 18 Feb, 2021
  • 1 location