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Found 37 clinical trials
Development of a Device for Evaluating Primary Hemostasis Under Whole Blood Flow Conditions (INDONESIA)

physiological conditions. An exploration of whole blood haemostasis in a device that is similar to a blood vessel and at different flow conditions (venous and arterial) could help to better identify the

von willebrand factor
Accepts healthy volunteers
antiplatelet drugs
  • 13 May, 2022
  • 2 locations
Rotational Thromboelastometry Versus DIC Score in Sepsis (RODSS)

Sepsis results in activation of the coagulation system, which is commonly described as disseminated intravascular coagulation (DIC). The DIC score, which is commonly used to define this syndrome, does not allow to delineate between hypercoagulation and hypocoagulation. The aim of this prospective observational study is to evaluate data from automated …

  • 10 Jul, 2022
  • 1 location
The "MyoThrombus" Study

Left ventricular thrombus is a recognised complication of acute myocardial infarction, associated with stroke, recurrent myocardial infarction and adverse cardiac remodelling. The prevention, treatment and resolution of thrombus is hampered by a lack of understanding of its initiation, propagation and dissolution. Advanced non-invasive imaging holds major promise in improving our …

  • 24 Apr, 2021
  • 1 location
Coagulopathy in Acute Aortic Syndrome

The existence of AAS coagulopathy has been reported, related to blood contact with the walls of the non-endothelialized false lumens. It is likely that endothelial dysfunction generated by vascular lesions may largely contribute to the development of coagulopathy, such as described in trauma-induced coagulopathy. This endotheliopathy of the AAS has …

  • 16 Dec, 2021
  • 1 location
Treatment of Hemophilia A Patients With FVIII Inhibitors

This is a non-interventional, multicenter, observational, international study in male persons with haemophilia A who have developed inhibitors to any replacement coagulation factor VIII (FVIII) product. The purpose of the study is to capture different approaches in the management of persons with haemophilia A and FVIII inhibitors, document current immune …

immune tolerance induction
antihemophilic factor
immune tolerance
coagulation factor
  • 04 Oct, 2022
  • 2 locations
Thrombosis in Patients With Multiple Myeloma in an University Medical Center (THRIMM)

Main research question: What is the present venous thrombosis incidence and what are the current practices of prescribing thromboprophylaxis in patients with multiple myeloma (MM)? Design The present study is a retrospective cohort study. The patients will be selected from the electronic patient dossier (EPD) of the University Medical Center …

  • 19 Oct, 2022
  • 1 location
COVID-19 Coagulopathy Extension Study

At the University of Iowa, the investigators led a multicenter randomized clinical trial comparing standard prophylactic dose to intermediate dose enoxaparin in hospitalized patients with COVID-19 (NCT04360824). As part of an exploratory biomarker component of this trial, blood samples were collected from hospitalized COVID-19 patients at enrollment and weekly for …

  • 04 Oct, 2022
  • 1 location