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Found 62 clinical trials
ABC - A Post Intensive Care Anaemia Management Trial

On discharge from intensive care (ICU) patients are often severely anaemic (have a low level of haemoglobin (Hb) in their red blood cells (RBC)). Anaemia can persist for many months making

  • 0 views
  • 07 Oct, 2022
  • 1 location
Double Blinded, Randomized, Placebo-controlled Parallel Investigation Into the Effects of Supplementing Y META, on Gut Health, Immunity and Metabolism in Pre-diabetic Adult Population (YMETA)

pre-diabetic state. People with pre-diabetes, defined as having impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or impaired glycated haemoglobin (HbA1c),2 are at increased risk of

  • 0 views
  • 07 Oct, 2022
  • 1 location
Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE) (PIPSICKLE)

PE in pregnant haemoglobin (Hb)SS women. The investigators also plan to build a machine-learning model to predict severe maternal outcomes in them. The investigators propose a multi-site

aspirin
Accepts healthy volunteers
fetal growth retardation
vasoconstrictor
  • 0 views
  • 05 Mar, 2022
  • 13 locations
Iron in Patients With Cardiovascular Disease (iCHF-2)

It is now recognized that iron deficiency in cardiovascular disease contributes to impaired clinical outcome.

haem
malnutrition
fibrillation
myocardial infarction
infarct
  • 15 views
  • 10 Feb, 2022
  • 1 location
Non Surgical Therapy of Periodontitis in Diabetes Patients: the Adjunctive Use of Probiotics (ProDiabet)

The aim of this study is to evaluate the clinical and microbiological performance of a probiotic formulation (Sunstar GUM Periobalance) as adjunctive to non-surgical periodontal therapy in patients with diabetes. The null hypothesis is that the adjunctive use of this probiotic formulation would not have any additional benefit over scaling …

root planing
osteopenia
Accepts healthy volunteers
debridement
diabetes
  • 43 views
  • 15 Jun, 2022
  • 1 location
Protein and Performance (PROPER) in Endurance Athletes (PROPER)

The present study is a parallel group design with randomised allocation to either a 1) reduced protein diet (RP) or a 2) normal protein diet (NP). The two groups will be pair-matched based on habitual dietary protein intake, endurance training, endurance performance, and sex. The aim of the study is …

Accepts healthy volunteers
  • 0 views
  • 14 Jul, 2022
  • 1 location
β-alanine Supplementation in Prediabetes

The study will investigate the safety, feasibility, and efficacy of beta-alanine supplementation in adults with prediabetes. Beta-alanine is a widely used dietary supplement that can increase the amount of carnosine in skeletal muscle. Both carnosine and beta-alanine occur naturally in animal food products and previous research shows that supplementation with …

hemoglobin a1c
body mass index
fasting
plasma glucose
sugars
  • 0 views
  • 30 Apr, 2022
  • 1 location
Vitamin D in School Children

The primary purpose of this study it to investigate total circulating 25-hydroxyvitamin D (25(OH)D) in school children (aged 4-11years) in Northern Ireland; thereby establishing the prevalence of vitamin D status (deficiency, insufficiency, and sufficiency (SACN 2016)) in this cohort. Additionally, the study aims to determine if 10g/day vitamin D3 supplementation …

  • 0 views
  • 02 Sep, 2021
  • 1 location
Role of Oxygen in the Development of Fatigue in Patients With Chronic Respiratory Failure (Oxyfatigue)

The literature on the physiological response (vasodilation, neuromuscular fatigue, and muscle oxygenation) following the application of different dosages of oxygen therapy in patients with Chronic Respiratory Failure (CRF) and Long-Term Oxygen Therapy (LTOT) during exercise is scant. The evaluation of these aspects can allow the clinicians and the rehabilitation staff …

  • 0 views
  • 07 Oct, 2022
  • 1 location
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations (BBESPB)

Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain. Development and implementation in clinical practice perioperative intensive care protocols for surgical correction of spinal deformities.

chronic pain
acute pain
bupivacaine
dexamethasone
anesthesia
  • 0 views
  • 07 Oct, 2022
  • 1 location