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Found 7 clinical trials
Hemlibra in Mild Hemophilia A

This is a single arm, phase 4, prospective, open-label, United States single-center study to determine the hemostatic characteristics of Hemlibra (emicizumab) as measured by coagulation laboratory parameters in the mild hemophilia A male patient population with endogenous altered FVIII (baseline FVIII activity of >5% to 30%). The safety and hemostatic …

  • 0 views
  • 21 Oct, 2021
  • 1 location
Use of Tranexamic Acid After Vaginal Delivery With Episiotomy a RCT Placebo Control Trail

The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.

Accepts healthy volunteers
  • 0 views
  • 15 Sep, 2022
  • 1 location
ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma (ARYA-2)

Open-label, dose escalation, multi-center, Phase I/II clinical trial to assess the safety/tolerability and determine the recommended Phase II Dose (RP2D) of ET140203 T-cells in pediatric subjects who are AFP-positive/HLA-A2-positive and have relapsed/refractory HB, HCN-NOS, or HCC.

measurable disease
carcinoma
  • 0 views
  • 27 Jul, 2022
The Effectiveness of Lactoferrin in the Management of Treatment-induced Anemia in Hematological Patients

This will be a randomised control trial designed to test the effectiveness of lactoferrin in the management of treatment-induced anemia in patients with hematological malignancies.

anemia
cancer
cyclophosphamide
epoetin alfa
erythropoietin
  • 14 views
  • 20 Sep, 2022
  • 2 locations
Effect of Paracetamol on Kidney Function in Severe Malaria (PROTECtS)

A randomised open labeled, parallel-group, controlled trial to assess the efficacy of paracetamol to reduce kidney dysfunction caused by cell-free haemoglobin-mediated oxidative damage in paediatric patients with falciparum malaria complicated by intravascular haemolysis.

  • 0 views
  • 05 Mar, 2022
Accuracy of Pulse CO-Oximetry Technology in Characterizing Noninvasive SpHb

This protocol is a request from Masimo to assist in the collection of data to be used to further refine the accuracy of the monitor's algorithm.

elective surgery
  • 0 views
  • 23 Mar, 2022
  • 1 location
ATHN 11: Liver Transplantation Outcomes Study (HOT)

This study is designed as a multi-center, observational cohort study of participants with hemophilia A and B who have and have not undergone liver transplantation. Participants will be asked to complete health related quality of life questionnaires and provide medical history.

liver transplant
  • 13 views
  • 21 Mar, 2022
  • 15 locations