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Found 24 clinical trials
Gene Therapy With GX-12 in Combination With HAART for the HIV-1 Infected Patients

The purpose of this study is to assess the safety of GX-12 gene therapy combined with HAART in the HIV-1 infected patients and to investigate the efficacy with the value of plasma viral

haart
  • 17 views
  • 07 Nov, 2020
  • 1 location
Pilot Study of Raltegravir Lipodystrophy IISP

the chronic use of NRTIs. Changing the HAART regimen in patients with a sustained virological response from a PI plus NRTI to a regimen of the PI plus raltegravir will likely result in

raltegravir
lipodystrophy
haart
  • 34 views
  • 08 Nov, 2020
  • 1 location
Xpert Ultra and Xpert HIV-VL in People Living With HIV

TB is increasingly diagnosed using the GeneXpert platform, which can be used for a variety of tests (not just TB). HIV viral load monitoring is required at least annually in patients on ART to detect failure of virologic suppression, however, most HIV VL testing is done in a central lab. …

hiv viral load
  • 107 views
  • 09 May, 2021
  • 1 location
Antiretroviral Therapy for Acute and Chronic HIV Infection

This is a protocol designed to randomize subjects with acute HIV infection to receive standard HAART or mega-HAART for subject who are enrolled in SEARCH 010 study (protocol title: Establish and

  • 8 views
  • 25 Jan, 2021
  • 1 location
SHARE: Simple HAART With Abacavir Reyataz and Epivir

SHARE: Simple HAART with Abacavir, Reyataz, and Epivir

antiretrovirals
norvir
ritonavir
epzicom
atazanavir
  • 8 views
  • 07 Nov, 2020
  • 1 location
Lopinavir/Ritonavir Monotherapy Versus Standard Highly Active Antiretroviral Therapy (HAART) in HIV/HCV Coinfected Patients Starting Treatment With Anti-Hepatitis C Virus (HCV) Therapy

The purpose of this study is to evaluate if the combination of Lpv/r monotherapy and anti-HCV drugs does not match with additional toxicity induced by the association of HAART and Peg-IFN

lopinavir
lopinavir/ritonavir
antiretroviral therapy
ritonavir
hepatitis
  • 13 views
  • 07 Nov, 2020
  • 1 location
Albuvirtide in Combination With 3BNC117 in Patients With Multi-Drug Resistant (MDR) HIV-1 Infection

The primary objectives are to assess the antiviral activity, clinical safety and tolerability parameters of albuvirtide/3BNC117 combination therapy in reducing HIV-1 viral load during the 1-week induction period treatment period.

  • 0 views
  • 30 Jan, 2021
  • 7 locations
7-valent Pneumococcal Conjugated Vaccination

Hypothesis: the efficacy of 2 doses 7-valent PCV is equivalent to 1 dose 7-valent PCV.

  • 0 views
  • 07 Nov, 2020
Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients

Early treatment of invasive fungal infections (IFI) may prevent undue mortality in acute on chronic liver failure (ACLF) patients. We aim to study the impact of early empiric treatment (based on clinical suspicion) of IFI as compared to pre-emptive treatment (based on biomarkers and culture positivity) on the outcomes in …

invasive fungal infections
fungal infection
invasive fungal infection
antibiotics
SIRS
  • 0 views
  • 21 Mar, 2021
  • 1 location
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Background Kaposi sarcoma (KS) is a cancer most often seen in people with HIV. It causes lesions. These are usually on the skin but sometimes in the lymph nodes, lungs, and gastrointestinal tract. Researchers think a combination of drugs may help treat KS. Objective To test a combination of the …

protease
AIDS
neutrophil count
systemic therapy
ct scan
  • 11 views
  • 01 Mar, 2021
  • 1 location