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Found 92 clinical trials
Enteral Zinc to Improve Growth in Infants at Risk for Bronchopulmonary Dysplasia

critical role in growth, through its actions on growth hormone, IGF-1, IGFBP-3, and bone metabolism. Prematurity is a risk factor for zinc deficiency, as 60% of zinc accretion occurs in the third trimester

very low birth weight
severe bronchopulmonary dysplasia
  • 21 Mar, 2022
  • 2 locations
Association of T Gamma Delta-CD16+ Cells and Anti-CMV Immunoglobulins in the Prevention of CMV Infection

> The humoral anti-CMV response is represented by the production of antibodies to envelope proteins (gB and gH) and to molecules involved in viral attachment and entry into target cells. However

kidney transplant
  • 26 Nov, 2021
  • 1 location
Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD (ASCENT ASD)

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

  • 16 May, 2022
  • 19 locations
Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures

This study evaluates the efficacy of the AuryzoN devices in the ear and nose reconstruction surgeries, both in terms of operative time and overall quality of reconstruction. Research participants will undergo reconstruction either using the AuryzoN device or through current methods (traditional manual processing) at the discretion of their surgeon …

  • 26 Feb, 2022
  • 1 location
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

total cavopulmonary connection
  • 04 Oct, 2022
  • 1 location
Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury

The aim of this clinical trial is to assess the efficacy of tesamorelin as a therapy for peripheral nerve injuries. The investigators hypothesize that treatment with tesamorelin will allow for faster and greater recovery of motor and sensory function following surgical repair of injured peripheral nerves. Patients with upper extremity …

nerve damage
Accepts healthy volunteers
  • 05 Mar, 2022
  • 1 location
The Impact of Exercise / Stress Stimuli on HMB Supplementation Efficacy

The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) free acid supplementation (90 mg/kg of fat free body mass/day) supplemented for 21 days on protein kinases activity and selected hormones levels, and subsequent improvements in muscle protein synthesis, lean body mass content and aerobic capacity.

Accepts healthy volunteers
  • 04 Oct, 2022
  • 2 locations
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) (DHAPS)

Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even death. The goal of this study is to prospectively compare two approaches to the postoperative …

hormone secreting
  • 20 Apr, 2022
  • 1 location
Understanding the Role of Gut Microbiota in Hyperphagia in Prader-Willi Syndrome (PWSGUT)

This study aims to use a high-fiber supplementation, an intervention known to create shifts in the gut microbiota towards a healthier structure, to explore the relationship between gut microbiota, appetite control and feeding behavior in PWS patients.

Accepts healthy volunteers
  • 11 Apr, 2023
  • 1 location
Differing Levels of Hypoglycemia

Hypoglycemia can produce a spectrum of pro-inflammatory and pro-atherothrombotic changes. To date no studies appear to have investigated the effects of differing levels of hypoglycemia on the vasculature and pro-atherothrombotic balance during hypoglycemia in healthy man. The specific aim of our study will be to determine the effects of differing …

body mass index
Accepts healthy volunteers
  • 22 Apr, 2022
  • 1 location