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Found 116 clinical trials
Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk

. Growth hormone is a hormone produced in the pituitary gland that helps regulate metabolism and growth. Individuals with obesity, on average, secrete less growth hormone than individuals without obesity

steatohepatitis
hepatic failure
hepatitis
vitamin
growth hormone
  • 3 views
  • 18 Feb, 2022
PK and PD Study of LUM-201 in Children With Growth Hormone Deficiency. (OraGrowtH212)

The goals of this single site trial are to study the pharmacokinetics (PK) and pharmacodynamics of LUM-201 and effects of LUM-201 administration on growth hormone release over time in children

  • 0 views
  • 23 Mar, 2022
Growth Hormone as a Model for Reversible Activation of Adipose Tissue Fibrosis

Background: Adipose tissue fibrosis denotes excessive pathological accumulation of extracellular matrix (ECM) in adipose tissue and is a marker of dysfunction. Growth hormone (GH) activates

  • 0 views
  • 10 Sep, 2021
  • 1 location
A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism

This clinical trial will use growth hormone as a novel treatment for Phelan-McDermid syndrome (PMS) and idiopathic autism. A double-blind, placebo-controlled crossover trial design will be used

  • 0 views
  • 15 Jun, 2022
Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

Background For children with gigantism, too much growth hormone (GH) in the body causes abnormal growth and many other problems. Current treatments often don t

medical therapy
hand x-ray
pituitary tumor
igf-i
growth hormone
  • 2 views
  • 14 Jun, 2022
  • 1 location
Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy

Patients with a history of mild traumatic brain injury (mTBI) or post acute sequelae of SARS-CoV-2 (PASC) and abnormal growth hormone secretion, as measured by glucagon stimulation test, will be

hormone therapy
somatropin
Accepts healthy volunteers
genotropin
growth hormone
  • 111 views
  • 13 May, 2022
  • 1 location
A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is

This research study will find out if a new growth hormone stimulation test is safe and works as well as other tests to diagnose growth hormone deficiency (GHD) in children. The stimulation test

  • 0 views
  • 25 Sep, 2021
  • 1 location
Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial (TRIIM-X)

, cardiovascular disease, diabetes, dementia, and also infectious diseases, including flu and COVID-19. The study uses multiple agents in combination with personalized doses of recombinant human growth

Accepts healthy volunteers
  • 146 views
  • 05 Mar, 2022
  • 1 location
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)

Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity and mortality rates for babies with congenital diaphragmatic hernia (CDH) remain high. The survival relates to the degree of prenatal lung compression and the …

nitric oxide therapy
pulmonary hypoplasia
diaphragmatic hernia
nitric oxide
MRI
  • 7 views
  • 14 Oct, 2021
  • 1 location
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia

The goal is to assess the feasibility and safety of implementing Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in fetuses with severe left Congenital Diaphragmatic Hernia (CDH) at UTHealth. UTHealth's success in this study (with an initial 5 patients) will determine the feasibility of UTHealth's future participation in multi-center trials of …

diaphragmatic hernia
pulmonary hypoplasia
  • 0 views
  • 11 Mar, 2021
  • 1 location