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Found 66 clinical trials
Severe Bullous Drug Eruption and Filgrastim (GNET)

blindness... The therapeutic potential of G-CSF (Granulocyte-Colony Stimulating Factor) in TEN is supported by several observations. The G-CSF promotes skin healing. This has been shown in

  • 13 Mar, 2022
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

since the description of ICL, its etiology, pathogenesis, and management remain unclear. In this study we propose to administer the combination of granulocyte colony stimulating factor (G-CSF) and

Accepts healthy volunteers
  • 28 Oct, 2022
  • 1 location
A Phase I Study of MozobilTM in the Treatment of Patients With WHIMS

medication called granulocyte colony stimulating factor (G-CSF), and supplemental immunoglobulin (antibody). These therapies are expensive, nonspecific, have significant side effects and toxicities, and do

cervical cap
white blood cell count
immune globulin
neutrophil count
  • 10 Oct, 2022
  • 1 location
Treatment and Natural History Study of Lymphomatoid Granulomatosis

beyond a maximum response, with six cycles minimum. To reduce harm to bone marrow, patients receive granulocyte colony stimulating factor (G-CSF), self-administered by injection under the skin daily for

hair loss
bone pain
  • 28 Oct, 2022
  • 1 location
Total Marrow and Lymphoid Irradiation and Chemotherapy for High-Risk Acute Leukemia

RATIONALE: Giving chemotherapy and total marrow and lymphoid irradiation before allogeneic hematopoietic cell transplant helps stop the growth of leukemia cells. It may also stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may …

lymphocytic leukemia
ejection fraction
myeloid leukemia
carbon monoxide
  • 22 Jan, 2021
  • 1 location
Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAML

Patients enrolled from each center according to confirmed criteria specified in cooperative scheme are recieved induction and consolidation chemotherapy with microtransplantation . Observe the remission rate and 2-year disease-free survival (DFS) and overall survival(OS) rate.

  • 13 Mar, 2022
  • 1 location
Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease (PISMO)

The objective of this study is to investigate if up to two injections of plerixafor represent a safe and effective strategy to mobilize adequate numbers of CD34+ hematopoietic stem progenitor cells (HSPC) for autologous hematopoietic cell transplantation (HCT) in sickle cell disease (SCD) patients

blood transfusion
doppler echocardiography
cell transplantation
  • 15 Mar, 2022
  • 1 location
Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

This phase II trial studies the outcomes of using a JAK inhibitor prior to reduced intensity haploidentical (Haplo) transplantation for the treatment of primary or secondary myelofibrosis (MF). Haplo transplant has been shown to be safe and effective in patients with leukemia and lymphoma who don't have an available sibling …

  • 06 Jun, 2022
  • 1 location
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

This phase I/II trial studies the side effects and best dose of a radioactive agent linked to an antibody (211At-BC8-B10) followed by donor stem cell transplant in treating patients with high-risk acute leukemia or myelodysplastic syndrome that has come back (recurrent) or isn't responding to treatment (refractory). 211At-BC8-B10 is a …

chronic myelomonocytic leukemia
white blood cell count
myeloproliferative syndromes
stem cell transplantation
  • 16 May, 2022
  • 1 location
Microtransplantation for Advanced and Relapsed Solid Tumors

In this study, we will apply micro transplantation to the field of solid tumors to study the efficacy and safety of radiotherapy and chemotherapy combined with micro transplantation in the treatment of advanced / relapsed solid tumors.

  • 01 Jul, 2021