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Found 79 clinical trials
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HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection

Heart transplantation is a life saving therapy for people with end stage heart failure. Acute rejection, a process where the immune system recognizes the transplanted heart as foreign and mounts a response against it, remains a clinical problem despite improvements in immunosuppressive drugs. Acute rejection occurs in 20-30% of patients …

Accepts healthy volunteers
blood test
heart failure
heart transplantation
  • 73 views
  • 28 Oct, 2021
  • 4 locations
None
Social & Contextual Impact on Children Undergoing Liver Transplantation

The social determinants of health have a large impact on health. For example, neighborhood socioeconomic deprivation is associated with increased risk of medication non-adherence, graft failure

liver transplant
  • 0 views
  • 12 Sep, 2021
  • 10 locations
None
Indications for Osteochondral Allograft Transplantation

performed. We will document all adverse events and complications, including joint or incision infection, graft failure, hardware failure, and arthrofibrosis. Patients with a VAS pain score >5 beyond 3

collapse
based products
range of motion
  • 3 views
  • 28 Oct, 2021
  • 1 location
None
Predicting Endoleaks Following Endovascular Aortic Aneurysm Repair Using 18F-Sodium Fluoride

The purpose of the study is to describe Sodium Fluoride uptake (using Positron Emission Tomography-Computed Tomography - PET-CT) following Endovascular Aneurysm Repair (EVAR) and to determine whether Sodium Fluoride PET-CT can predict the development of endoleaks.

  • 0 views
  • 05 May, 2021
  • 4 locations
None
Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis

The purpose of this research study is to see how effective hematopoietic stem cell transplantation (HCT) is compared to best available non-transplant therapies (BAT) in patients with high risk myelofibrosis. This will be done by asking participants to choose the treatment that they prefer to receive (HCT or BAT) and …

stem cell transplantation
thrombocytosis
hydroxyurea
polycythemia
essential thrombocythemia
  • 0 views
  • 24 Feb, 2021
  • 6 locations
None
The Role of Hepcidin as a Biomarker to Predict Successful Renal Transplantation

High hepcidin concentrations indicate that iron is blocked from secretion from the reservoir. Hepcidin may be useful in prediction functional iron utilization in renal failure patients. Hepcidin is also associated with chronic renal failure and residual renal function in dialysis patients. Recent studies have shown that hepcidin is a potential …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Target Busulfan Exposure in Children With HSCT in China

Objectives To evaluate the correlation between BU exposure and post-transplant clinical results (efficacy and safety) to establish the optimal BU treatment window for myeloablative conditioning in Chinese pediatrics, provide theoretical basis and the new strategy for BU individualized dosage, further optimize transplant treatment and reduce drug-related toxicity. Population 500 participants …

  • 0 views
  • 19 Mar, 2021
  • 1 location
None
An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR

The aim of this trial is to collect data and provide a better understanding of the long-term outcome of imlifidase treatment on active or chronic active antibody-mediated rejection (AMR) in kidney transplant recipients. This is done by collecting data during an extended follow-up period of 3 years of clinical study …

  • 0 views
  • 05 Nov, 2021
  • 3 locations
None
Cf-DNA Assay During Treatment of Acute Rejection

The objective of this study is to determine whether cell-free DNA (cf-DNA) measurement can be used as a biomarker for successful treatment of an acute rejection (AR) episode after kidney transplantation. A fall in donor cf-DNA level may be a biomarker for successful AR treatment. The goal is to do …

kidney transplant
cfdna
  • 2 views
  • 10 May, 2021
  • 1 location