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Found 87 clinical trials
Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Background Blood stem cells in the bone marrow make all the cells to normally defend a body against disease. Allogeneic blood or marrow transplant is when these stem cells are transferred from one person to another. Researchers think this treatment can provide a new, healthy immune system to correct T-cell …

bone marrow procedure
mesna
thrombocytopenia
chest x-ray
neutropenia
  • 138 views
  • 17 Jun, 2022
  • 2 locations
Cancer Rehab Program for Allogenic Bone and Marrow Transplant Patients - CaRE-4-alloBMT

Currently, transplantation centers across North America generally do not offer longitudinal rehabilitation programs and research is urgently needed to test the acceptability and effectiveness of these programs using innovative delivery strategies that have the potential for future scalability and to understand the associated costs. Through a strong collaboration between the …

cancer
  • 0 views
  • 09 Oct, 2021
  • 1 location
Timing of Glaucoma Drainage Device With Boston Keratoprosthesis

Boston keratoprosthesis (KPro) is a piece of specialized plastic that replace sick cornea (transparent structure at the front of the eye) in patients who have failed or those who are expected to have poor results with traditional corneal transplantation. While the Kpro can offer dramatic improvement in vision, it is …

drainage
brimonidine tartrate ophthalmic solution
neuropathy
blindness
glaucoma
  • 23 views
  • 25 Sep, 2021
  • 2 locations
Reduced Intensity BMT for Immune Dysregulatory and Bone Marrow Failure Syndromes Using Post-Transplant Cyclophosphamide

This is a Phase II prospective trial to assess the rates of donor engraftment using reduced intensity conditioning (RIC) hematopoietic stem cell transplant (HSCT) and post-transplant cyclophosphamide (PTCy) for patients with primary immune deficiencies (PID), immune dysregulatory syndromes (IDS), and inherited bone marrow failure syndromes (IBMFS).

hla-a
forced vital capacity
immunoglobulin
immunoglobulin e
thrombocytopenia absent radii
  • 0 views
  • 24 Feb, 2022
  • 1 location
Romidepsin Maintenance After Allogeneic Stem Cell Transplantation

The goal of this clinical research study is to learn if giving romidepsin before and after a stem cell transplant in combination with fludarabine and busulfan can help to control leukemia or lymphoma. Researchers also want to learn the highest tolerable dose of romidepsin that can be given with this …

lymphoid leukemia
fludarabine
prolymphocytic leukemia
leukemia
t-cell lymphoma
  • 122 views
  • 03 May, 2022
  • 1 location
A Clinical Study to Investigate Interferon Gamma (IFN ) Signature in Patients Post HSCT and in Patients With Impaired HSC Proliferation Pre-transplant

production is impaired. The blood samples will be used to study the role of Interferon gamma (IFN) in graft failure or impairment of hematopoietic stem cell proliferation. The IFN signature will be assessed

  • 0 views
  • 02 Jun, 2021
  • 25 locations
Superior Capsular Reconstruction With InternalBrace Study (SCRIB)

The aim of the study is to investigate the clinical and radiological outcomes after superior capsular reconstruction with InternalBrace (SCRIB) performed for irreparable rotator cuff tears.

Accepts healthy volunteers
  • 0 views
  • 13 May, 2022
Clinical Database Associated With a Biological Banking Accessible to Initiate Epidemiological and Translational Collaborative Researches in Kidney Transplantation

until the graft failure, at each scheduled outpatient visit or hospital admission motivating by a new clinical, therapeutical or biological expression. The DIVAT cohort contains information on more

graft failure
  • 45 views
  • 21 Jan, 2021
  • 8 locations
VIRTUUS Children's Study (VIRTUUS)

The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.

kidney transplant
  • 31 views
  • 15 Feb, 2022
  • 12 locations
Treatment of Graft Failure After Hematopoietic Stem Cell Transplantation

This is a guideline for the treatment of graft failure after hematopoietic stem cell transplant (HSCT). This regimen, consisting of cyclophosphamide and fludarabine with low dose total body

  • 0 views
  • 02 May, 2022
  • 1 location