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Found 80 clinical trials
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LifeNet: Extracellular Matrix Graft in Rotator Cuff Repair

This trial is to evaluate the effectiveness of the ArthroFLEX ECM scaffold graph as an augment in rotator cuff repair surgery to reduce the failure rate of rotator cuff repairs for large and massive rotator cuff tears.

rotator cuff repair
  • 10 views
  • 02 May, 2021
  • 1 location
None
Low Dose ATG Plus Low Dose PTCy as GVHD Prophylaxis in Haplo-HSCT

Low dose Rabbit Antithymocyte Globulin plus Low-dose post-transplantation cyclophosphamide as graft-versus-host disease prophylaxis in haploidentical hematopoietic stem cell transplantation for patients with hematologic malignancies

lymphocyte immune globulin
cell transplantation
cyclophosphamide
hla-a
cancer
  • 6 views
  • 23 Jan, 2021
  • 1 location
None
Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

This clinical trial studies the effect of pre-transplant immunosuppression (PTIS) and donor stem cell transplant in treating patients with severe blood diseases (hemoglobinopathies). PTIS helps prepare the body for the transplant and lowers the risk of developing graft versus host disease (GVHD). Hematopoietic cells are found in the bone marrow …

electrophoresis
tacrolimus
osteonecrosis
hemoglobinopathy
acute chest syndrome
  • 0 views
  • 01 Nov, 2021
  • 1 location
None
High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) affects white blood cell function. Currently, the only curative treatment is bone marrow transplant to replace the abnormal stem cells with new ones (donor cells) capable of making a normal immune system. Transplant problems include graft versus host disease (GvHD) and graft rejection. With GvHD, donor …

  • 3 views
  • 01 Dec, 2021
  • 1 location
None
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Background Allogeneic blood or marrow transplant is when stem cells are taken from one person s blood or bone marrow and given to another person. Researchers think this may help people with immune system problems. Objective To see if allogeneic blood or bone marrow transplant is safe and effective in …

hypogammaglobulinemia
graft versus host disease
Accepts healthy volunteers
pulmonary function tests
blood test
  • 446 views
  • 05 Dec, 2021
  • 2 locations
None
Eltrombopag for People With Fanconi Anemia

Background Fanconi anemia is a genetic disease. Some people with it have reduced blood cell counts. This means their bone marrow no longer works properly. These people may need blood transfusions for anemia (low red blood cells) or low platelet counts or bleeding. Researchers want to see if a new …

eltrombopag
platelet count
chromosome breakage
danazol
cytopenia
  • 162 views
  • 25 Nov, 2021
  • 1 location
None
PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

This is a phase III, multicenter, randomized, open label, clinical trial to test that hypothesis that plasmapheresis plus rituximab prior to kidney transplantation can prevent recurrent FSGS in children and adults.

monoclonal antibodies
arrhythmias
cancer
proteinuria
focal segmental glomerulosclerosis
  • 83 views
  • 01 Dec, 2021
  • 14 locations
None
Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Background Blood stem cells in the bone marrow make all the cells to normally defend a body against disease. Allogeneic blood or marrow transplant is when these stem cells are transferred from one person to another. Researchers think this treatment can provide a new, healthy immune system to correct T-cell …

graft versus host disease
Accepts healthy volunteers
pulmonary function tests
anesthesia
bone marrow procedure
  • 138 views
  • 05 Dec, 2021
  • 2 locations
None
Stent vs. Angioplasty for Treatment of Thrombosed AV Grafts: Long-Term Outcomes

Arteriovenous grafts are used as the vascular access in 40-50% of hemodialysis patients. Grafts are prone to recurrent stenosis (narrowing) and thrombosis (clotting). Graft clotting is usually due to a narrowing at the site where the graft joins the vein. The standard treatment is to remove the clot and angioplasty …

stent placement
dialysis
av graft
  • 2 views
  • 07 Nov, 2020
  • 1 location
None
Cancer Rehab Program for Allogenic Bone and Marrow Transplant Patients - CaRE-4-alloBMT

Currently, transplantation centers across North America generally do not offer longitudinal rehabilitation programs and research is urgently needed to test the acceptability and effectiveness of these programs using innovative delivery strategies that have the potential for future scalability and to understand the associated costs. Through a strong collaboration between the …

cancer
  • 0 views
  • 09 Oct, 2021
  • 1 location