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Found 80 clinical trials
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Femtolaser Assisted Keratoplasty Versus Conventional Keratoplasty

biomechanically stronger cornea and thereby more safety and less risk of wound dehiscence? Is there any difference between FLAK and conventional keratoplasty in terms of graft failure or rejection?

corrected visual acuity
penetrating keratoplasty
resistance factor
corneal transplant
intraocular pressure
  • 16 views
  • 28 Jan, 2021
  • 1 location
None
Comparison of New-onset Diabetes After Transplantation Between Two Steroid Withdrawal Group With CellCept

transplantation (NODAT) is a common complication of solid-organ transplantation, and is a strong predictor of graft failure and cardiovascular mortality in the transplant population. Risk factors for NODAT in

insulin resistance
insulin
  • 0 views
  • 08 Nov, 2020
  • 1 location
None
CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

The purpose of this study is to learn more about the effects of (classification determinant) CD34+ stem cell selection on graft versus host disease (GVHD) in children, adolescents, and young adults. CD34+ stem cells are the cells that make all the types of blood cells in the body. GVHD is …

chronic myeloid leukemia
busulfan
lymphocytic leukemia
graft versus host disease
myeloid leukemia
  • 79 views
  • 01 Nov, 2021
  • 1 location
None
Targeted Busulfan Fludarabine Etoposide Conditioning Regimen for HSCT in Childhood and Adolescent ALL.

To evaluate the outcome of hematopoietic stem cell transplantation using targeted busulfan, fludarabine, etoposide conditioning regimen in childhood and adolescent ALL.

ejection fraction
cell transplantation
transplant conditioning
busulfan
etoposide
  • 14 views
  • 26 Jun, 2021
  • 1 location
None
Hematopoietic Cell Transplantation for Patients With Hematologic Malignancies Using Related HLA-Haploidentical Donors

The purpose of this study is to determine if engraftment can be achieved safely in patients with high-risk hematologic malignancies who undergo non-myeloablative transplant with peripheral stem cells from Human Leukocyte Antigen (HLA) haploidentical donors with pre and post-transplant cyclophosphamide as immunosuppression.

cell transplantation
immunosuppressant
cancer
graft versus host disease
cyclophosphamide
  • 19 views
  • 07 Oct, 2021
  • 1 location
None
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

In this study, the investigators test 2 dose levels of thiotepa (5 mg/kg and 10 mg/kg) added to the backbone of targeted reduced dose IV busulfan, fludarabine and rabbit anti-thymocyte globulin (rATG) to determine the minimum effective dose required for reliable engraftment for subjects undergoing hematopoietic stem cell transplantation for …

malignant disease
busulfan
graft versus host disease
hemophagocytic lymphohistiocytosis
pulse oximetry
  • 176 views
  • 19 Oct, 2021
  • 1 location
None
A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD

HSCT is currently the only curative option for SCD but less than 20% of SCD patients have a MD donor available. So far, all curative approaches beyond a MSD HSCT at young age are non-satisfactory. With the lack of a suitable donor for the vast majority of patients, the major …

cell transplantation
priapism
osteonecrosis
chest syndrome
stroke
  • 0 views
  • 08 Aug, 2021
  • 5 locations
None
Fludarabine Based RIC for Bone Marrow Failure Syndromes

This is a pilot study to determine whether fludarabine-based reduced intensity conditioning (RIC) regimens facilitate successful donor engraftment of patients with acquired aplastic anemia (AA) and Inherited bone marrow failure (iBMF) syndromes undergoing Matched related donor bone marrow transplant (MRD-BMT).

  • 0 views
  • 23 Jul, 2021
  • 1 location
None
Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

This phase II trial studies how well donor peripheral blood stem cell (PBSC) transplant works in treating patients with hematologic malignancies. Cyclophosphamide when added to tacrolimus and mycophenolate mofetil is safe and effective in preventing severe graft-versus-host disease (GVHD) in most patients with hematologic malignancies undergoing transplantation of bone marrow …

forced expiratory volume
autograft
graft versus host disease
multiple myeloma
tyrosine
  • 25 views
  • 22 Jul, 2021
  • 2 locations
None
Role of Double Cuffed PTFE Arteriovenous Grafts in Enhancing Long-term Patency in Hemodialysis Patients (Extended Poly Tetra Fluoro Ethylene)

this randomized controlled trial will compare the double vein cuffed synthetic arteriovenous graft to the single vein cuffed synthetic and the non cuffed synthetic as regard to long-term patency of each modality

arteriovenous graft
nephropathy
  • 16 views
  • 22 Jan, 2021
  • 1 location