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Found 140 clinical trials
Older Adult Effectiveness of 2 Treatments

viscosity glass-ionomer cement (GIC) (GC Fuji Automix LC Resin Reinforced Glass Ionomer Restorative, Japan)). Patients will also receive biannual topical fluoride varnish treatments (FluoriMax, Elevate

Accepts healthy volunteers
fluoride
arrest
  • 0 views
  • 10 Mar, 2022
  • 1 location
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

in the percentage of patients experiencing an objective response in the setting of advanced unresectable or metastatic gastric cancer or gastro-esophageal junction adenocarcinoma (GC/GEJ), especially

squamous cell carcinoma
carcinoma
cancer
esophageal cancer
pembrolizumab
  • 0 views
  • 07 Oct, 2022
  • 39 locations
STI/HIV Intervention Behavioral Intervention Program

The hypothesis is that a behavioral intervention tool adapted for the US military population will be acceptable and associated with a decrease in incident sexually transmitted infection (STI)/HIV rates and high-risk sexual behaviors, and increased self-reported condom use compared to the standard of care at the Joint Base Lewis-McChord (JBLM) …

Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 2 locations
S-1 for 9 Months Versus 1 Year for Stage II Gastric Cancer (SMAC)

The study aims to compare the efficacy and safety of S-1 for 9 months versus S-1 for 1 year as adjuvant chemotherapy after D2 resection in patients with gastric cancer. Hypothesis: For gastric patients after D2 resection, S-1 for 9 months shows non-inferiority to S-1 for 1 year in disease-free …

cancer chemotherapy
adjuvant chemotherapy
lymphadenectomy
adenocarcinoma
immunostimulants
  • 0 views
  • 07 Feb, 2022
  • 6 locations
Genetic Testing in Young Adults With Cancer Study

The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …

primary cancer
cancer diagnosis
solid tumor
genetic testing
  • 0 views
  • 20 Oct, 2021
  • 1 location
Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device

The purpose of this academic-industrial partnership will be to compare two thermoablation modalities using devices adapted to low and middle income countries (LMICs) to traditional CO2-based cryotherapy for the treatment of cervical precancer. The investigators will investigate whether the cure rates of cervical intraepithelial neoplasia 2 and more severe diagnoses …

cervical intraepithelial neoplasia grade 2
cervical high grade squamous intraepithelial lesion
cervical dysplasia
cin 3
cryotherapy
  • 0 views
  • 04 Oct, 2022
  • 3 locations
A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women

To achieve an AIDS-free generation, there is a critical need for programs which go beyond individual-level behavior change to reduce HIV and STI infections among adolescent girls and young women in sub-Saharan Africa. Informed, Motivated, Aware, and Responsible Adolescents and Adults (IMARA) is an evidence-based HIV-prevention intervention for adolescent girls …

pre-exposure prophylaxis (prep)
AIDS
hiv test
HIV Vaccine
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Improving Antibiotic Use in Urgent Care Facilities (SCORE_UC)

This study will implement a comprehensive outpatient stewardship program targeting a large network of Urgent Care (UC) clinics within Intermountain Helathcare.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
Vitamin D Supplementation in the Armed Forces (D_SAF)

The study will comprise of an original investigation that will take the form of a prospective intervention (two matched groups) study. Condition-1 will be a vitamin D supplementation group (50.000 IU every two months), and Condition-2 will be a placebo supplementation group. The primary research aim of this project is …

serum pth
vitamin
vitamin d supplementation
stress fracture
Accepts healthy volunteers
  • 59 views
  • 08 Feb, 2022
  • 1 location
Perioperative Immunotherapy vs. Chemo-immunotherapy in Patients With Advanced GC and AEG (IMAGINE)

IMAGINE is a Phase II, randomized, two-arm, chemotherapy controlled modular trial in subjects with histologically confirmed, resectable gastric cancer (GC) or adenocarcinoma of the

neutrophil count
cancer
international normalized ratio
renal function
adenocarcinoma of the gastroesophageal junction
  • 2 views
  • 19 Feb, 2022
  • 1 location