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Found 156 clinical trials
Zoliflodacin in Uncomplicated Gonorrhoea

of a single intra-muscular 500 mg dose of ceftriaxone and a single 1 g oral dose of azithromycin for the treatment of uncomplicated gonorrhoea.

azithromycin
zoliflodacin
ceftriaxone
nucleic acid amplification test
hiv testing
  • 43 views
  • 21 Feb, 2022
  • 12 locations
A Phase II Randomized, Observer-Blind, Placebo-Controlled Study, to Assess the Efficacy of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) in Preventing Gonococcal Infection

the study is to demonstrate efficacy of Bexsero in prevention of urogenital and/or anorectal gonococcal infection.

Accepts healthy volunteers
  • 107 views
  • 21 Oct, 2022
  • 7 locations
A Phase III, Randomized, Multicenter, Open-Label Study in Adolescent and Adult Participants Comparing the Efficacy and Safety of Gepotidacin to Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae

This is a phase III, randomized, multicenter, open-label study which will be performed to evaluate efficacy and safety of oral Gepotidacin compared to intramuscular (IM) ceftriaxone plus oral azithromycin for the treatment of uncomplicated urogenital infection caused by Neisseria gonorrhoeae (N. gonorrhoeae) in adolescent and adult subjects. In this study, …

gepotidacin
neisseria gonorrhoeae
ceftriaxone
azithromycin
  • 32 views
  • 28 Oct, 2022
  • 38 locations
A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH

An investigation of the efficacy and safety of up to 70 weeks of treatment with Tildacerfont in subjects with classic CAH who have elevated biomarkers at baseline on their current GC regimen

17-hydroxyprogesterone
deficiency
prednisone
prednisolone
21-ohd
  • 28 views
  • 07 Oct, 2022
  • 57 locations
Brief Intervention to Reduce STDs in ER Drug Users - 1

The purpose of this study is to test whether a brief motivational interview focused on sexual practices will facilitate behavior change, risk reduction and reduced rate of sexually transmitted infections among emergency department patients who use heroin and cocaine and are out-of-treatment for their substance abuse.

heroin
motivational interviewing
  • 48 views
  • 07 Nov, 2020
  • 1 location
Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention

gonorrhea among a cohort of HIV-positive and high risk HIV-negative men. Investigators plan to test the following hypotheses: Participants will maintain a high level of adherence and

  • 0 views
  • 17 Jun, 2022
  • 1 location
Mucosal Immune Responses Against Neisseria Gonorrhoeae Following Meningococcal Immunization in Healthy Young Adults

, and the length of the study is estimated for 14 months. The primary objective is to characterize the rectal mucosal Immunoglobulin G IgG antibody response to Neisseria gonorrhoeae (GC) elicited by the

Accepts healthy volunteers
  • 0 views
  • 23 Oct, 2022
  • 1 location
Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae

meningitidis infections, also protects from Neisseria gonorrhoeae infection using controlled human experimental infection to test protection. The information the investigator learn by doing this study may also

Accepts healthy volunteers
  • 10 views
  • 05 Jun, 2022
  • 1 location
HLX07+HLX10+Chemotherapy or HLX07 Monotherapy in Patients With Advanced Metastatic Gastric Cancer

This study is conducted in patients with advanced metastatic gastric cancer including gastroesophageal junction cancer. This study includes two arms: A and B. Arm A (patients with HER2 negative and PD-L1 CPS≥5 ) will receive HLX07 combination therapy with HLX10 and chemotherapy (oxaliplatin+capecitabine) as first-line treatment. Arm B will receive …

  • 0 views
  • 16 May, 2022
  • 2 locations
Acute Consequences Of Food-induced Glucocorticoid Secretion In Healthy Individuals (Gluco-Feed)

In a randomized, cross-over study, 20 healthy volunteers will receive a block and replace therapy that mimics physiological GC rhythm (metyrapone plus hydrocortisone) or placebo. Participants

Accepts healthy volunteers
  • 0 views
  • 21 Apr, 2022
  • 1 location