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Found 19 clinical trials
Intensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGET

ulcerative colitis who failed corticosteroids and immunosupressive therapy, or are intolerant to immunosuppressors. All included patients will be nave to anti-TNF therapy. Active disease at golimumab

golimumab
prednisone
azathioprine
mesalamine
corticosteroids
  • 2 views
  • 27 May, 2019
  • 19 locations
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

rheumatoid arthritis. Etanercept is a fusion protein with TNF receptor type II p75 and IgG1 Fc fragment, whereas adalimumab, infliximab, and golimumab are monoclonal antibodies. Certolizumab is a fusion

biological therapy
NSAID
fusion protein
steroidal anti-inflammatory drugs
enthesitis
  • 17 views
  • 24 Jan, 2021
  • 26 locations
A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate efficacy of golimumab in inducing clinical remission as assessed by the Mayo score, in pediatric participants with moderately to severely active

endoscopy
azathioprine
sigmoidoscopy or colonoscopy
corticosteroids
methotrexate
  • 53 views
  • 04 Dec, 2020
  • 85 locations
A Study of Efficacy and Safety of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the clinical efficacy and safety of combination therapy with guselkumab and golimumab in participants with moderately to severely active ulcerative

golimumab
  • 65 views
  • 17 Jan, 2021
  • 160 locations
GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA (GOLMEPsA)

An investigator-initiated double-blind, parallel-group randomised controlled trial of GOLimumab and Methotrexate versus Methotrexate in very early PsA using clinical and whole body MRI outcomes

  • 0 views
  • 23 Jan, 2021
  • 1 location
Golimumab for the Treatment of Refractory Behcet's Uveitis

The aim of this single-center prospective study is to evaluate the efficacy and safety of Golimumab GOL, fully humanized anti-tumor necrosis factor (TNF)- monoclonal antibody, in the treatment

tumor necrosis factor
immunosuppressant
uveitis
behcet's syndrome
monoclonal antibodies
  • 1 views
  • 23 Jan, 2021
  • 1 location
Golimumab in Ulcerative Colitis (UC) Patients With Loss of Response (LOR) Followed by Dose Optimization

It is planned to enroll 80 UC patients who will require optimization of golimumab after secondary LOR. The review of the study protocol and its approval by an Independent Ethics Committee of the

endoscopy
golimumab
  • 6 views
  • 16 Jan, 2021
  • 5 locations
A Study to Evaluate SIMPONI (Golimumab) Therapy in Children Adolescents and Young Adults With Pre-Symptomatic Type 1 Diabetes

The purpose of this study is to determine the safety and tolerability of golimumab in children, adolescents, and young adults with pre-symptomatic stage 2 type 1 diabetes mellitus (T1D).

  • 32 views
  • 04 Dec, 2020
  • 10 locations
A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis

The purpose of this study is to assess the safety of subcutaneous (SC) golimumab in participants with active Ankylosing Spondylitis (AS) or Psoriatic Arthritis (PsA) over 24 weeks.

arthritis
NSAID
steroidal anti-inflammatory drugs
rheumatoid nodules
spondyloarthropathy
  • 96 views
  • 31 Dec, 2020
  • 12 locations
Identification of Predictive Biomarkers for Response to Biologic Therapies in Inflammatory Bowel Disease

Prospective, multicentre trial which the biologic treatment will be initiated by clinical indication. The treatment selection anti-TNF (infliximab, adalimumab or golimumab), vedolizumab and

tumor necrosis factor alpha
adalimumab
intestinal diseases
luminal
corticosteroids
  • 32 views
  • 24 Jan, 2021
  • 15 locations