Found 54 clinical trials
Sensitivity and Specificity of TSA-CBA for Autoantibodies Against Neural Antigen Determination (STAND)
of neuromyelitis optica spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), autoimmune encephalitis (AE). Cell based assay (CBA) has been frequently
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- 03 Jul, 2022
- 1 location
MS-ResearchBiomarkerS (MS-ReBS)
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information from visual assessment, blood markers, as well as historical and ongoing longitudinal MRIs of the brain, orbit (the part of the skull …
- 0 views
- 26 Mar, 2022
- 1 location
Non-invasive Identification of Colorectal Cancer and Adenomas in Early Stages (NICE)
The NICE study is a prospective, multi-site study to train and validate a blood-based, glycoproteomic test for the early detection of advanced adenoma and colorectal cancer by collecting blood samples and associated relevant clinical information from average-risk participants who undergo routine screening colonoscopy as well as participants undergoing colonoscopy for …
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- 04 Oct, 2022
- 12 locations
International Milk Composition (IMiC) Consortium (IMiC)
The IMiC Consortium will analyze milk from 1000 mother-infant dyads across 4 diverse settings (Tanzania, Pakistan, Burkina Faso and Canada). Samples will be stored centrally at the Manitoba Interdisciplinary Lactation Centre (MILC) biorepository and distributed to multiple laboratories for analysis of macronutrients, micronutrients, oligosaccharides, growth factors, immunoglobulins, cytokines, metabolites and …
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- 30 May, 2022
- 1 location
Precision Medicine in the Treatment of Epilepsy (BDE)
Primary objectives: The purpose of this study is to identify single and composite biomarkers (from neuroimaging, electrophysiological, and non-imaging biological measures), clinical measures (from cognitive, psychometric, and behavioral test scores), and risk/protective factors (e.g., from medical history, socioeconomic status, coping, lifestyle) that can: Predict antiseizure medication (ASM) treatment outcome, psychiatric, …
- 0 views
- 07 Oct, 2022
- 1 location
Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders
This study will evaluate children with glycosphingolipid (GSL) storage disorders to investigate brain changes that cause nervous system degeneration. No experimental treatments are offered in this study; participants will receive standard medical care for their disease. The information from this study may help researchers develop new therapies for these disorders …
- 76 views
- 25 Oct, 2022
- 1 location
Immunoglobulin M (IgM)-Anti-myelin-associated-glycoprotein(MAG) Peripheral Neuropathy Study
There is no international consensus regarding how to assess and treat patients with immunoglobulin M (IgM)-anti-myelin-associated-glycoprotein (MAG) monoclonal gammopathy associated peripheral
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- 07 Apr, 2022
Real-world Evidence on Follitropin Delta Individual Dosing
for a wide range of applications and is dosed individually according to body weight and serum anti-Müllerian hormone (AMH). Body weight is used to estimate the distribution volume of the glycoprotein
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- 21 Mar, 2022
- 1 location
Laboratory and Clinical Data in Antiphospholipid Patients
To constitute a registry of antiphospholipid antibodies positive-patients
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- 28 Dec, 2021
- 1 location
The "MyoThrombus" Study
Left ventricular thrombus is a recognised complication of acute myocardial infarction, associated with stroke, recurrent myocardial infarction and adverse cardiac remodelling. The prevention, treatment and resolution of thrombus is hampered by a lack of understanding of its initiation, propagation and dissolution. Advanced non-invasive imaging holds major promise in improving our …
- 0 views
- 24 Apr, 2021
- 1 location