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Found 125 clinical trials
Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation (Dapa-LiT)

transplantation. As these patients receive oral glucocorticoids (mostly prednisolone) and immunosuppressants, which elevate blood glucose levels, multiple doses of insulin are usually required. After 2-3 months

insulin
sitagliptin
hypoglycemic agents
oral hypoglycemic
metformin
  • 0 views
  • 24 Mar, 2022
  • 1 location
Clinical Study of MMF in Treatment of IIM-ILD and Its Effect on Peripheral Blood Treg Cells

challenging.At present, according to the consensus of IIM-ILD experts, glucocorticoids as first-line treatment are often used in high doses and have a variety of adverse reactions. Previous studies have shown

vasculitis
cyclophosphamide
myopathy
interstitial lung disease
forced vital capacity
  • 0 views
  • 30 Nov, 2021
  • 1 location
Clinical Treatment of Alopecia Areata With Stem Cell Educator Therapy and Oral Minoxidil

glucocorticoids and induction of allergic contact dermatitis. These therapies are not effective for many patients and are generally impractical for patients with diffuse AA, AT or AU. Recently, Janus kinase (JAK

  • 0 views
  • 18 Oct, 2022
Efficacy and Safety of an Innovative Chinese Herbal Formula for the Treatment of Gout: A Double-blind, Randomized, Placebo-Controlled Trial

, complex, and poorly understood. Thus, gout remains one of the major therapeutic challenges. Currently, western medicine treatment of gout flare includes colchicine, NSAIDs and glucocorticoids. These drugs

  • 0 views
  • 22 Oct, 2022
  • 1 location
Baricitinib in Patients With Relapsing or naïve Dermatomyositis (BIRD)

corticosteroids but this exposes patients to adverse events (cardiovascular mortality, glucocorticoids-induced muscle and skin damages). Corticosteroids taper is associated with disease relapses. Although there

corticosteroids
disease modifying antirheumatic drugs
dermatomyositis
methotrexate
glucocorticoids
  • 0 views
  • 07 Oct, 2022
  • 1 location
MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial (METOGiA)

> Glucocorticoids (GC) are the cornerstone of the treatment of GCA. They are very effective and are usually given for 18-24 months to avoid relapses. Therefore, most patients develop GC-related

tenderness
positron emission tomography
vasculitis
methotrexate
headache
  • 4 views
  • 30 May, 2022
  • 1 location
Umbilical Cord Mesenchymal Stem Cells as First-line Treatment for Patients With Acute Graft Versus Host Disease

Allogenic haemopoietic stem cell transplantation (allo-HSCT) is the effective treatment for many hematologic malignancies and some non-malignant diseases. In recent years, with the rapid improvement of economy and medical level, the number of cases of hematopoietic stem cell transplantation (HSCT) develops rapidly in China. In 2019, 12,323 cases of HSCT …

  • 0 views
  • 07 Oct, 2022
  • 1 location
The Effects of Preoperative High-dose Dexamethasone on Inflammatory Response and Recovery After Emergency Laparotomy, a Randomized, Double-blind, Placebo-controlled Clinical Trial - AHA STEROID TRIAL

The aim of this trial is to evaluate the effect of high-dose glucocorticoid on inflammatory response and recovery after emergency laparotomy in participants with intestinal obstruction and perforated viscus. Primary outcome is the reduction of C-reactive protein on postoperative day 1. Secondary outcomes are organ specific complications in the post …

inflammatory response
  • 0 views
  • 27 Oct, 2022
  • 1 location
Study of Mepolizumab-based Regimen Compared to Conventional Therapeutic Strategy in Patients With Eosinophilic Granulomatosis With Polyangiitis (E-merge) (E-merge)

The purpose of this study is to compare mepolizumab-based regimen to conventional therapeutic strategy for remission induction in patients with Eosinophilic Granulomatosis with Polyangiitis.

  • 0 views
  • 11 Jul, 2022
  • 1 location
Effect of Prednisolone Treatment on Uterine Natural Killer Cells

This study aims to investigate the role of uNK cells and its association with prednisolone.

natural killer cells
prednisolone
Accepts healthy volunteers
  • 6 views
  • 14 Feb, 2022
  • 1 location