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Found 125 clinical trials
Predictive Factors for Treatment Response in Patients With Newly-diagnosed Polymyalgia Rheumatica and Giant Cell Arteritis

This prospective study is to explore different predictive factors for response to steroid treatment in patients with PMR and/or GCA. It evaluates the association of endogenous GC suppression (plasma and urinary cortisol and cortisone) to the responsiveness of PMR/GCA to GCs.

  • 04 Oct, 2022
  • 1 location
Glucocorticoid Withdrawal Syndrome in Patients With Treated Cushing Syndrome

Cushing syndrome (CS) is an endocrine disorder caused by chronic exposure to glucocorticoid (GC) excess. Endogenous CS has an estimated incidence of 0.2 to 5.0 cases per million per year and prevalence of 39 to 79 cases per million in various populations. CS usually affects young women, with a median …

  • 02 Nov, 2021
  • 1 location
Stress-associated Epigenetic Alterations in Newborns After Fetal Surgery

Open spina bifida or myelomeningocele (MMC) is a devastating congenital defect of the central nervous system for which there is no cure. The etiology of MMC remains poorly understood. Primary failure of neural tube closure at the caudal neuropore in the embryonic period results in exposure of the developing spinal …

Accepts healthy volunteers
  • 13 Feb, 2022
  • 1 location
Omeprazole and Famotidine in Chronic Dysfunction of the Transplanted Kidney

The aim of the study is to compare the effect of omeprazole and famotidine on the risk of developing chronic renal transplant dysfunction. For the study, it is planned to qualify 36 stabilized adult patients from 1-24 months after kidney transplantation, who will receive p.o. the standard, most commonly used …

  • 20 Oct, 2021
A Hospital-at-Home Pilot in Singapore

Hospital-at-home models seek to address the impending shortage of hospital beds by reimagining the way we deliver acute hospital-level care - substituting the ward for a patient's home. Such programmes have been well established in other countries such as Australia, Europe and USA to be a less costly way to …

  • 16 Apr, 2021
  • 2 locations