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Found 121 clinical trials
A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

This study aims to define the efficacy and safety of inebilizumab for the prevention of flare of IgG4-related disease (IgG4-RD).

  • 0 views
  • 23 Apr, 2022
  • 70 locations
A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

An investigation of the ability of Tildacerfont to reduce supraphysiologic glucocorticoid dosing in classic CAH subjects up to 76 weeks of treatment.

deficiency
21-ohd
  • 10 views
  • 12 Mar, 2022
  • 38 locations
Evaluation of Glucocorticoids Plus Rituximab Compared to Glucocorticoids Plus Placebo for the Treatment of Patients With Newly-Diagnosed or Relapsing IgA Vasculitis (RIGA)

sequelae, especially in adults. The treatment of adult-onset IgAV is still a matter of debate. Glucocorticoids have been the standard of care for inducing remission for years in severe forms of IgAV

  • 0 views
  • 29 Apr, 2022
  • 1 location
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids

drugs called glucocorticoids (GCs) can calm down an overactive immune system. But they often cause negative side effects. Researchers want to learn how human genes respond to GCs. Genes live inside each

Accepts healthy volunteers
  • 0 views
  • 10 May, 2022
  • 1 location
Open Label Two-Arm Study to Evaluate Rilzabrutinib (PRN1008) in IgG4-Related Disease Patients

glucocorticoids and (2) Active Comparator: glucocorticoids only.

  • 7 views
  • 22 Jan, 2022
  • 3 locations
Deflazacort vs. Prednisolone in Acute-stage ABPA

Oral glucocorticoids are currently the treatment of choice for allergic bronchopulmonary aspergillosis (ABPA). They not only suppress the immune hyperfunction but are also anti-inflammatory

  • 199 views
  • 23 Feb, 2022
  • 1 location
Bioequivalence Study of Prednisolone and Dexamethasone (CORE)

The purpose of this study is to compare two different glucocorticoids, prednisolone and dexamethasone at two different doses for their organ specific effects, utilizing modern day standards.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
  • 0 views
  • 25 Mar, 2022
Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis. (MAINEPSAN)

glucocorticoids treatment. In a systematic review and meta-analysis, glucocorticoids regimen was the most significant variable explaining the variability between the proportions of ANCA-associated

  • 0 views
  • 15 Feb, 2022
  • 20 locations
Dexamethasone in Refractory or First Relapsed Acute Myeloid Leukemia

regrowth and relapse. Moreover, it has been experimentally shown that leukemic cells in acute myeloid leukemia patients who relapse become sensitive to glucocorticoids treatment highlighting a novel

  • 0 views
  • 25 Jan, 2021
  • 5 locations