Found 96 clinical trials
Treating PCOS With Semaglutide vs Active Lifestyle Intervention
Girls with obesity and polycystic ovarian syndrome will receive either glucagon like peptide-1 receptor agonist therapy or a dietary intervention for 12 weeks to decrease the metabolic syndrome
- 239 views
- 04 Oct, 2022
- 1 location
A Study of Tirzepatide (LY3298176) in Adults With Type 2 Diabetes Switching From a GLP-1 RA (SURPASS-SWITCH-2)
The main purpose of this study is to investigate the effects of switching from glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy to tirzepatide glucose-dependent insulinotropic
- 0 views
- 04 Apr, 2023
- 13 locations
Brain Activation and Satiety in Children 2
behavioral treatment (FBT) with a drug intervention using a glucagon-like peptide-1 receptor agonist (GLP-1RA) exenatide once weekly extended-release (ExQW, Bydureon) in order to improve obesity intervention
- 0 views
- 09 Sep, 2021
- 1 location
Effects of GRA in Patients With Type 1
This study will examine the effects a Glucagon Receptor Antagonist (GRA), has on Insulin Sensitivity, Cardiovascular risks (CVD), and Ketone body formation in participants with Type 1 diabetes
- 0 views
- 07 Oct, 2021
- 1 location
Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes (HISTORI)
To investigate whether the Glucagon Like Peptide 1 (GLP-1) Semaglutide (1.34 mg/ml) has preventive effect compared to placebo in the development of diabetes and Metabolic Syndrome in people with
- 0 views
- 22 Mar, 2022
- 1 location
GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response
This project investigates the anti-obesity mechanisms of glucagon-like peptide-1 (GLP-1) analogs, which are used in the treatment of human obesity and diabetes mellitus. The investigators will
- 280 views
- 22 Oct, 2022
- 1 location
Evaluating the Benefits of Physiologic Insulin Delivery
will inject ultra-rapid acting insulin into the upper and lower peritoneum under ultrasound guidance and compare it to subcutaneous injection. We will measure glucose, insulin and glucagon following
- 0 views
- 18 May, 2022
- 1 location
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
This project uses both transcriptomic- and genomic-level data to identify mechanisms of individual responses to glucagon-like peptide-1 (GLP-1) in Mexican-Americans with prediabetes. The GLP-1
- 1 views
- 21 Nov, 2021
- 1 location
Whey or Casein - Liver Fat Reduction and Metabolic Improvement by Fast vs. Slow Proteins (MOCA)
energy expenditure by urea synthesis, suppression of glucagon or other mechanisms. Up to now, it is unclear, if proteins with slower or faster digestibility lead to differential results in these study
- 30 views
- 04 Oct, 2022
- 1 location
Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3457263 Alone and in Combination With GLP-1 RA in Patients With Type 2 Diabetes
The main purpose of this study is to investigate the safety and tolerability of the study drug LY3457263 when administered alone or in combination with glucagon-like peptide 1 (GLP-1) receptor
- 0 views
- 28 Oct, 2022
- 3 locations