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Found 144 clinical trials
Dapagliflozin After Transcatheter Aortic Valve Implantation

Pragmatic, controlled, prospective, randomized, open-label (open-label), evaluator-blind clinical trial (PROBE design) that will analyze the benefits of dapagliflozin treatment in patients with severe aortic stenosis discharged after implantation of an aortic valve prosthesis transcatheter (TAVI).

  • 0 views
  • 04 Mar, 2021
  • 18 locations
A Phase 2b Diabetic Kidney Disease Study

A Phase 2b Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of MEDI3506 in Subjects with Diabetic Kidney Disease

nephropathy
diabetic nephropathy
  • 54 views
  • 25 Jan, 2021
  • 71 locations
Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

The study is designed as a multicenter, randomized , double-blind, placebo controlled study to demonstrate the superiority of LNP023 at a dose of 200 mg b.i.d. compared to placebo on top of maximally tolerated ACEi or ARB on reduction of proteinuria and slowing renal disease progression in primary IgA Nephropathy …

  • 0 views
  • 07 Mar, 2021
  • 18 locations
A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA Nephropathy

To determine the long-term (approximately 2 years) nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blocker in patients with immunoglobulin A nephropathy (IgAN).

angiotensin
immunoglobulin a
mammogram
proteinuria
nephropathy
  • 209 views
  • 02 Mar, 2021
  • 278 locations
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden. Currently, many Veterans with CKD have poor awareness of their condition. This leads to suboptimal care. The investigators anticipate that …

dialysis
nephropathy
renal failure
  • 0 views
  • 26 Jan, 2021
  • 1 location
Aspirin to Target Arterial Events in Chronic Kidney Disease

This study aims to find out whether people with chronic kidney disease [CKD] should take low dose aspirin to reduce the risk of first heart attack or stroke (cardiovascular disease [CVD]). CKD is common and is associated with an increased risk of CVD. CVD is caused by small blood clots …

stroke
aspirin
nephropathy
clot
chronic disease
  • 0 views
  • 23 Jan, 2021
  • 1 location
Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance

Evaluation of glomerular filtration rate using iohexol plasma clearance in critically ill patients with augmented renal creatinine clearance

  • 0 views
  • 07 Mar, 2021
  • 1 location
Eplerenone in Patients Undergoing REnal Transplant (EPURE TRANSPLANT)

evaluated by the measurement of glomerular filtration rate at 3 months - variable strongly associated with long-term graft survival.

chronic haemodialysis
glomerular filtration rate
kidney transplant
  • 24 views
  • 23 Jan, 2021
  • 8 locations
The Effects of Mycophenolate Mofetil (MMF) on Renal Outcomes in Advanced Immunoglobulin A (IgA) Nephropathy Patients

excretion and the changes in estimated glomerular filtration rate.

hypertension
losartan
glomerulosclerosis
immunoglobulin a
nephropathy
  • 17 views
  • 07 Mar, 2021
  • 3 locations
Comparison of Tacrolimus Extended-Release (Envarsus XR) to Tacrolimus Immediate-Release in HLA Sensitized Kidney Transplant Recipients

-specific HLA antibodies, estimated glomerular filtration rate, and the level of donor-derived cell-free DNA.

tacrolimus
rituximab
cfdna
glomerular filtration rate
envarsus xr
  • 0 views
  • 27 Jan, 2021
  • 1 location