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Found 145 clinical trials
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)

Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric hypertension and related target organ injury, including in the heart, kidneys, vasculature, and brain. Recruiting children with a new hypertension diagnosis over a …

renin
Uric Acid Test
hypertension
aldosterone
angiotensin
  • 0 views
  • 03 Jun, 2021
  • 1 location
Transformative Research in Diabetic Nephropathy

This is a prospective, observational, cohort study of patients with a clinical diagnosis of diabetes who are undergoing clinically indicated kidney biopsy. The intent is to collect, process, and study kidney tissue and to harvest blood, urine and genetic materials to elucidate molecular pathways and link them to biomarkers that …

nephropathy
diabetic nephropathy
kidney biopsy
diabetes
  • 316 views
  • 08 Mar, 2021
  • 23 locations
Myocardial Injury Following Non-cardiac Surgery

It is estimated that > 200 million patients in the world undergo surgery each year of which approximately 10 million will suffer from a myocardial injury in the perioperative period. Mortality is high in patients with myocardial injury since it often goes undiagnosed and management is unclear. In contrast to …

heart surgery
artery disease
troponin
infarct
myocardial infarction
  • 1 views
  • 02 Mar, 2021
  • 1 location
Intraoperative Phlebotomies and Bleeding in Liver Transplantation

Liver transplantation are surgeries associated with important bleeding and often require perioperative red blood cell (RBC) transfusions. Overall, between 20 and 85 % of liver transplant recipients receive at least one RBC transfusion during their surgery. Such transfusions are consistently associated with higher morbidity and mortality, although this causal association …

  • 0 views
  • 09 May, 2021
  • 1 location
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction

An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability. Large hernias contain large amounts of abdominal volume, which similarly are missing from the abdominal cavity. Due to adaptations of the abdominal …

tension
incisional hernia repair
abdominoplasty
incisional hernia
open surgery
  • 0 views
  • 24 Jan, 2021
  • 1 location