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Found 144 clinical trials
FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP)

Hereditary hypophosphatemia encompasses rare genetic conditions characterized by renal phosphate wasting. Increased circulating levels of fibroblast growth factor 23 (FGF23), a key regulator of phosphorus metabolism, are critical to the pathophysiology of these diseases, most notably in X-linked hypophosphatemia (XLH). Increased FGF23 induces hypertrophy and scarring in the heart in …

fgf-23
angiotensin
fibroblast growth factor 23
renin
kidney disease
  • 0 views
  • 03 Mar, 2021
  • 1 location
Role of NGAL and Cystatin C in Prediction of Acute Kidney Injury Covid-19 Infection

Recent different biomarkers of acute kidney injury (AKI) have been manufactured by pharmaceutical industry. Studies proved that Neutrophil gelatinase-associated lipocalin (NGAL) and cystatin c are effective predictive biomarkers for early acute kidney injury in septic patients and in children after cardiopulmonary bypass. This study hypothesize that both cystatin c and …

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Study on Kidney Disease and EnviromenTal Chemical

Purpose: To confirm the changes in lifestyle due to differences in perceptions of infectious disease risk after the COVID-19 pandemic, decrease in exposure levels of environmentally hazardous chemicals and changes in indicators related to chronic kidney disease Methods: Survey on health risk awareness and lifestyle for COVID-19 Blood and urine …

  • 0 views
  • 27 Jan, 2021
  • 1 location
The Tongue Features Associated With Chronic Kidney Disease

The Automatic Tongue Diagnosis System (ATDS) was developed to capture tongue images and extract features reliably to assist the diagnosis of TCM practitioners.This project will employ the ATDS verified to extract the tongue features of patients with chronic kidney disease(CKD) including dialysis patients. A TCM indices derived through the non-intrusive …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Hybrid Closed-Loop Insulin Delivery System in Type 1 Diabetes Candidates for a Living Donor Kidney Transplant

The investigators' primary aim is to determine the impact of using hybrid closed-loop (HCL) system in patients with type 1 diabetes (T1D) and end stage renal disease (ESRD) prior to kidney transplantation. The investigators will also determine whether HCL, by improving glucose control, will affect short-term (1 month) and long-term …

  • 0 views
  • 23 Jan, 2021
CT Perfusion Added to CT Angiography

Background In the differential diagnosis of unstable angina versus non-anginal chest pain, an exercise test is often the modality of choice for further investigation. However, in a substantial number of patients exercise testing is less informative, because of insufficient exercise capacity or pre-existing ECG-abnormalities. In patients with low pretest probability …

unstable angina
stenosis
chest pain
ct scan
angiography
  • 36 views
  • 26 Jan, 2021
  • 1 location
Screening Patients With Diabetes Mellitus for the Presence of Skin Disorder of Scleredema

Scleredema is a scleroderma-like skin disorder appearing in 2.5-14% among patients with type 1 or 2 diabetes mellitus. This is a single centre study to screen consecutive patients with diabetes mellitus for the presence of scleredema,and to compare the clinical-laboratory data of patients with and without scleredema. Metabolic and vascular …

diabetes mellitus
diabetes
  • 3 views
  • 24 Jan, 2021
  • 4 locations
The German ADPKD Tolvaptan Treatment Registry

The German ADPKD Tolvaptan Treatment Registry is a prospective, observational, multicentric study of patients suffering from ADPKD that are considered for tolvaptan treatment. All ADPKD patients that are evaluated for treatment indication, or that are planned to be treated with tolvaptan, or that are already treated with tolvaptan are eligible. …

  • 23 views
  • 15 Feb, 2021
  • 12 locations
Cirrhosis Effects of TRAnsplantation and Diabetes

This observational study is aimed at assessing insulin secretion and sensitivity by the use of a mathematical modeling from oral glucose tolerance test in subjects with liver cirrhosis undergoing orthotopic liver transplantation (OLT), before and at various time points after OLT.

cirrhosis
liver transplant
insulin
  • 3 views
  • 21 Jan, 2021
  • 2 locations
Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabetes

This project will assess the independent predictors of impaired muscle and bone strength through a longitudinal observation of a cohort of subjects with type 1 and 2 diabetes consecutively attending an outpatients diabetes clinics for the annual screening of complications.

diabetes
  • 7 views
  • 23 Jan, 2021
  • 1 location