Found 145 clinical trials
Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia
The purpose of this study is to evaluate the change in serum (blood) potassium levels from start of treatment to Day 14, when patiromer is administered at different doses, once daily, in children 2 - < 18 years of age with chronic kidney disease (CKD) and hyperkalemia (too much potassium …
- 476 views
- 10 Jun, 2021
- 46 locations
Study of the Anti-FGF23 Antibody Burosumab in Adults With XLH
This is phase 3b open-label, international, multicenter study to continue to monitor the long-term safety and efficacy of burosumab in adult patients with XLH that participated in previous clinical trials with burosumab (UX023-CL303 / UX023-CL304).
- 32 views
- 23 Jan, 2021
- 11 locations
Twice Against Thrice-weekly Hemodialysis
Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue. In the majority of developed Western and Asian countries, patients on chronic hemodialysis are undergoing three dialysis sessions weekly. In developing countries and some developed …
- 23 views
- 26 Jan, 2021
- 1 location
Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients
The objective of this study is to examine the effect on allograft function and histology of converting African American renal transplant recipients with chronic allograft nephropathy (CAN) from a tacrolimus-based regimen to a sirolimus-based maintenance immunosuppression regimen. The investigators hypothesize that the conversion from tacrolimus to sirolimus in African American …
- 20 views
- 08 Nov, 2020
- 1 location
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
: incidence of tumors and cardiovascular events. The primary objective: To assess if superior graft function (glomerular filtration rate (GFR) difference of 10 ml/min) will be achieved at 1 year
- 18 views
- 07 Nov, 2020
- 4 locations
Pilot Study: Interest of Belatacept as a Non-nephrotoxic Immunosuppressive Treatment in Cardiac Transplant Patients at Risk of Chronic Renal Failure (BELACOEUR)
risk factors for progression to CKD are advanced age, pre-transplantation CKD, degradation of glomerular filtration rate (GFR) in the first year post-transplantation, and nephrotoxicity of calcineurin
- 0 views
- 02 May, 2021
- 5 locations
Viral Load Guided Immunosuppression After Lung Transplantation
(TTV viral load in whole blood) compared to conventional calcineurin inhibitor dosing. Indicator for toxicity will be the glomerular filtration rate (GFR), which will be estimated using the CKD-EPI
- 0 views
- 03 Jun, 2021
- 2 locations
Effect of Empagliflozin on Urinary Excretion of Adenosine and Osteocyte Function in Patients With Chronic Kidney Disease
, which may contribute to the excessive glomerular filtration rate as a result of vasodilation of the afferent vessels. Adenosine, unlike other vascular regions, increases the tension in the walls of the
- 0 views
- 25 Jul, 2021
- 1 location
Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing
Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.
- 0 views
- 24 Jan, 2021
- 1 location