Found 142 clinical trials
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Multi-country trial
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Accepting Seniors
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Accepting adults
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For all genders
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Currently Recruiting
A PHASE 3 TRIAL OF THE EFFICACY AND SAFETY OF BARDOXOLONE METHYL IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
="text-decoration: underline;">Primary: - To assess the change from baseline in estimated glomerular filtration rate (eGFR) at Week 52 following a 4-week drug
- 63 views
- 23 Nov, 2020
- 2 locations
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Phase 4 trial
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Accepting pediatric ages
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Accepting adults
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For females only
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Currently Recruiting
Do You Have Osteoporosis?
Do You Have Osteoporosis?
- 1122 views
- 25 Mar, 2021
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Long-term Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) With Venglustat
> Secondary Objective: To determine the effect of early versus delayed treatment with venglustat on the renal function (estimated glomerular filtration rate [eGFR]). To characterize
- 0 views
- 05 Mar, 2021
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients
Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in
- 82 views
- 02 Apr, 2021
- 130 locations
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Multi-country trial
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia
The purpose of this study is to evaluate the change in serum (blood) potassium levels from start of treatment to Day 14, when patiromer is administered at different doses, once daily, in children 2 - < 18 years of age with chronic kidney disease (CKD) and hyperkalemia (too much potassium …
- 476 views
- 15 Feb, 2021
- 46 locations
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Study of the Anti-FGF23 Antibody Burosumab in Adults With XLH
This is phase 3b open-label, international, multicenter study to continue to monitor the long-term safety and efficacy of burosumab in adult patients with XLH that participated in previous clinical trials with burosumab (UX023-CL303 / UX023-CL304).
- 32 views
- 23 Jan, 2021
- 11 locations
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Twice Against Thrice-weekly Hemodialysis
Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue. In the majority of developed Western and Asian countries, patients on chronic hemodialysis are undergoing three dialysis sessions weekly. In developing countries and some developed …
- 23 views
- 26 Jan, 2021
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients
The objective of this study is to examine the effect on allograft function and histology of converting African American renal transplant recipients with chronic allograft nephropathy (CAN) from a tacrolimus-based regimen to a sirolimus-based maintenance immunosuppression regimen. The investigators hypothesize that the conversion from tacrolimus to sirolimus in African American …
- 20 views
- 08 Nov, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Nephrology
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Currently Recruiting
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
: incidence of tumors and cardiovascular events. The primary objective: To assess if superior graft function (glomerular filtration rate (GFR) difference of 10 ml/min) will be achieved at 1 year
- 18 views
- 07 Nov, 2020
- 4 locations
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Multi-country trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Viral Load Guided Immunosuppression After Lung Transplantation
(TTV viral load in whole blood) compared to conventional calcineurin inhibitor dosing. Indicator for toxicity will be the glomerular filtration rate (GFR), which will be estimated using the CKD-EPI
- 0 views
- 26 Jan, 2021
- 2 locations