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Found 143 clinical trials
Do You Have Osteoporosis?

Do You Have Osteoporosis?

  • 25 Mar, 2021
  • 1 location
Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia

The purpose of this study is to evaluate the change in serum (blood) potassium levels from start of treatment to Day 14, when patiromer is administered at different doses, once daily, in children 2 - < 18 years of age with chronic kidney disease (CKD) and hyperkalemia (too much potassium …

  • 10 Jun, 2021
  • 46 locations
Study of the Anti-FGF23 Antibody Burosumab in Adults With XLH

This is phase 3b open-label, international, multicenter study to continue to monitor the long-term safety and efficacy of burosumab in adult patients with XLH that participated in previous clinical trials with burosumab (UX023-CL303 / UX023-CL304).

  • 23 Jan, 2021
  • 11 locations
Twice Against Thrice-weekly Hemodialysis

Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue. In the majority of developed Western and Asian countries, patients on chronic hemodialysis are undergoing three dialysis sessions weekly. In developing countries and some developed …

chronic renal failure
chronic hemodialysis
renal replacement therapy
  • 26 Jan, 2021
  • 1 location
Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients

The objective of this study is to examine the effect on allograft function and histology of converting African American renal transplant recipients with chronic allograft nephropathy (CAN) from a tacrolimus-based regimen to a sirolimus-based maintenance immunosuppression regimen. The investigators hypothesize that the conversion from tacrolimus to sirolimus in African American …

  • 08 Nov, 2020
  • 1 location
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation

: incidence of tumors and cardiovascular events. The primary objective: To assess if superior graft function (glomerular filtration rate (GFR) difference of 10 ml/min) will be achieved at 1 year

calcineurin inhibitor
  • 07 Nov, 2020
  • 4 locations
Pilot Study: Interest of Belatacept as a Non-nephrotoxic Immunosuppressive Treatment in Cardiac Transplant Patients at Risk of Chronic Renal Failure (BELACOEUR)

risk factors for progression to CKD are advanced age, pre-transplantation CKD, degradation of glomerular filtration rate (GFR) in the first year post-transplantation, and nephrotoxicity of calcineurin

  • 02 May, 2021
  • 5 locations
Viral Load Guided Immunosuppression After Lung Transplantation

(TTV viral load in whole blood) compared to conventional calcineurin inhibitor dosing. Indicator for toxicity will be the glomerular filtration rate (GFR), which will be estimated using the CKD-EPI

  • 03 Jun, 2021
  • 2 locations
Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing

Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.

  • 24 Jan, 2021
  • 1 location
Clinical Study of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Type 2 Diabetic Nephropathy

The study was a 48-week multicenter, randomized, double-blind, placebo-controlled trial that included 8 weeks of pre-screening and lifestyle education, 32 weeks of treatment, and 16 weeks of follow-up.To observe the efficacy and safety of umbilical cord mesenchymal stem cell infusion in Chinese patients with type 2 diabetic nephropathy who received …

  • 27 Jan, 2021
  • 1 location