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Found 510 clinical trials
Infigratinib in Recurrent High-Grade Glioma Patients

This trial is an open-label, multicenter, Phase 0 trial that will enroll up to 20 participants with recurrent high-grade glioma with FGFR1 K656E or FGFR3 K650E mutation or FGFR3-TACC3

amylase
calcium
FGFR1
neutrophil count
recurrent malignant glioma
  • 0 views
  • 28 Jan, 2021
  • 3 locations
PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma (PRiME)

The primary goal of this prospective clinical trial is to evaluate the safety of PEP-CMV in patients with recurrent medulloblastoma and malignant glioma. Patients with histologically-proven

brain mri
neutrophil count
chemoradiotherapy
MRI
karnofsky performance status
  • 22 views
  • 19 Jun, 2022
  • 1 location
Personalized Vaccine for Patients With Recurrent Malignant Glioma

malignant glioma.

malignant glioma
recurrent malignant glioma
measurable disease
  • 8 views
  • 05 Jul, 2021
  • 1 location
Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma

Childhood aggressive gliomas are rare brain tumors with very poor prognosis. Due to the tumor's location and infiltrative nature, surgical removal is not always possible, and even when resection

  • 0 views
  • 28 Sep, 2021
  • 1 location
Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma

This is a pilot study to assess a new methodology developed for High Grade Glioma (HGG). FMISO PET (Fluoromisonidazole-PET) allows researchers to study whether tumor cells lack oxygen (hypoxia

vascular endothelial growth factor
EGFR
MRI
cancer
vegf
  • 0 views
  • 20 Apr, 2022
  • 1 location
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma

This is a study of DSP-0390 in patients with recurrent high grade glioma.

corticosteroids
sargramostim
aptt
dexamethasone
  • 5 views
  • 06 May, 2022
  • 4 locations
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

any, these drugs have on children and young adults with brain tumors. The investigators are asking people to be in this research study who have been diagnosed with a high grade glioma (HGG

malignant glioma
dipg
anticonvulsants
glioblastoma multiforme
renal function
  • 2 views
  • 20 Sep, 2022
  • 9 locations
A Study on -elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas

to delay tumor growth, or impact how long people with newly diagnosed high-grade glioma.

  • 0 views
  • 22 Jan, 2021
  • 1 location
Seizure Treatment in Glioma (STING)

Currently, treatment with a specific anti-epileptic drug mainly depends on the physicians' preference, as there are no studies supporting the use of one specific anticonvulsant in glioma

anaplastic astrocytoma
oligodendroglioma, anaplastic
epilepsy
anaplastic oligodendroglioma
levetiracetam
  • 9 views
  • 28 Feb, 2022
  • 4 locations
Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas

without anti-PDL1 antibody) personalized immunotherapy for patients with recurrent malignant gliomas based on the expression of tumor specific/associated antigens (EGFRVIII, IL13R2, Her-2, EphA2, CD133

malignant glioma
karnofsky performance status
immunohistochemistry
erbb2
growth factor
  • 13 views
  • 26 Feb, 2022
  • 1 location