Found 330 clinical trials
A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) (PNOC020)
newly diagnosed GBM (MGMT unmethylated). Funding Source - FDA OOPD
- 0 views
- 07 Oct, 2022
- 1 location
Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients
In this phase I/II trial, the primary objective is to determine overall and progression-free survival of patients with newly diagnosed glioblastoma when autologous Wilms' tumor 1 (WT1) messenger
- 34 views
- 28 Jan, 2021
- 1 location
Phase 2 Study of CAN008 in Subjects With GBM
therapy in newly-diagnosed subjects with glioblastoma who have undergone surgical excision.
- 4 views
- 04 Oct, 2022
- 1 location
SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)
glioblastoma. This study is designed to compare the length of survival in patients with newly diagnosed glioblastoma who receive temozolomide plus SurVaxM to that of patients treated with standard-of-care
- 21 views
- 07 Oct, 2022
- 10 locations
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma
Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be
- 0 views
- 04 Oct, 2022
- 1 location
Effectiveness of MR-guided LITT Therapy in Irresectable Glioblastoma (EMITT) (EMITT)
The aim of this study is to investigate the (cost-)effectiveness of LITT (Laser Interstitial Thermal Therapy) in primary irresectable glioblastoma. Glioblastoma are the most common malignant
- 0 views
- 30 Apr, 2022
- 1 location
Irinotecan And Bevacizumab Combined With Re-radiotherapy in Recurrent Glioblastoma
This is a phase I study to observe the safety and efficacy of irinotecan and bevacizumab combined with re-radiotherapy in the treatment of recurrent glioblastoma. The study will provide a higher
- 0 views
- 25 Mar, 2022
- 1 location
Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG)
The study will investigate combined stereotactic radiosurgery and enhanced immunotherapy for recurrent glioblastomas. Immune adjuvants will be injected intratumorally and systemically to induce
- 0 views
- 29 Nov, 2021
- 1 location
Personalized Functional Profiling in Metastatic Gastrointestinal Cancer or Recurrent Glioblastoma Patients in Luxembourg.
The investigators are developing a novel standardized and centralized approach named Integrated Personalized Functional Profiling (PFP) in Luxembourg. Based on recent improvements in cancer biopsy-derived 3D-culture technologies the PFP process will screen patient derived cells (PDCs) with FDA/EMA-approved drugs to generate personalized functional response profiles. The selected drug through PFP …
- 4 views
- 16 Mar, 2022
- 2 locations
Neoadjuvant PD-1 Antibody Alone or Combined With DC Vaccines for Recurrent Glioblastoma
Glioblastoma multiforme (GBM) are the most prevalent malignant tumor in central nervous system. At recurrence, no clear standard-of-care therapy is agreed for recurrent GBM (rGBM) and median
- 0 views
- 08 Dec, 2021
- 1 location