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Found 351 clinical trials
Featured trial
Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblatoma (GBM) or other primary CNS tumors with an activating FGFR1-3 mutation or fusion/rearrangement. This study consists of 3 cohorts, Cohorts A, B, and C, and will enroll approximately 82, 82, and 25 participants into each cohort, respectively. …

  • 0 views
  • 25 May, 2022
  • 1 location
Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM

glioblastoma (rGBM) undergoing carboplatin monotherapy.

glioblastoma multiforme
tumor progression
  • 14 views
  • 15 Dec, 2021
  • 4 locations
The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.

The study is to evaluate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy for patients with maligant glioblastoma multiforme. Autologous TiLs should be given by intravenous

  • 0 views
  • 30 Apr, 2022
  • 1 location
Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients

In this phase I/II trial, the primary objective is to determine overall and progression-free survival of patients with newly diagnosed glioblastoma when autologous Wilms' tumor 1 (WT1) messenger

  • 33 views
  • 28 Jan, 2021
  • 1 location
Anlotinib Combined With STUPP for MGMT Nonmethylated Glioblastoma

The purpose of this study is to test the efficacy and safety of Anlotinib in combination with STUPP regimen for MGMT promoter nonmethylated glioblastoma.

  • 4 views
  • 28 Jan, 2021
  • 1 location
Irinotecan And Bevacizumab Combined With Re-radiotherapy in Recurrent Glioblastoma

This is a phase I study to observe the safety and efficacy of irinotecan and bevacizumab combined with re-radiotherapy in the treatment of recurrent glioblastoma. The study will provide a higher

  • 0 views
  • 25 Mar, 2022
  • 1 location
Individualized Systems Medicine Functional Profiling for Recurrent Glioblastoma

A study to determine the feasibility and safety of individualized cancer stem cell targeted therapy based on high-throughput functional profiling of FDA/EMA-approved drugs in patients with GBM that has recurred or progressed following standards-of-care (RT, TMZ).

  • 0 views
  • 20 Sep, 2021
  • 1 location
Effectiveness of MR-guided LITT Therapy in Irresectable Glioblastoma (EMITT) (EMITT)

The aim of this study is to investigate the (cost-)effectiveness of LITT (Laser Interstitial Thermal Therapy) in primary irresectable glioblastoma. Glioblastoma are the most common malignant

  • 0 views
  • 30 Apr, 2022
  • 1 location
SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)

glioblastoma. This study is designed to compare the length of survival in patients with newly diagnosed glioblastoma who receive temozolomide plus SurVaxM to that of patients treated with standard-of-care

  • 0 views
  • 14 May, 2022
  • 5 locations
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be

  • 0 views
  • 24 May, 2022
  • 1 location