Found 358 clinical trials
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209) (FIGHT-209)
This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblatoma (GBM) or other primary CNS tumors with an activating FGFR1-3 mutation or fusion/rearrangement
- 3 views
- 22 Oct, 2022
- 27 locations
Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM
glioblastoma (rGBM) undergoing carboplatin monotherapy.
- 14 views
- 15 Dec, 2021
- 4 locations
GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) Patients
The purpose of this study is to evaluate the efficacy and safety of GX-I7 in combination with bevacizumab in subjects with recurrent glioblastoma.
- 0 views
- 04 Oct, 2022
- 1 location
The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.
The study is to evaluate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy for patients with maligant glioblastoma multiforme. Autologous TiLs should be given by intravenous
- 0 views
- 30 Apr, 2022
- 1 location
Combined Treatment of Camrelizumab and Bevacizumab for Adult Patients With Recurrent Glioblastoma (GBM)
This study is intend to explore the efficacy and safety of combined treatment of camrelizumab and bevacizumab in adult patients with recurrent glioblastoma.
- 0 views
- 17 Jul, 2021
- 1 location
B7-H3 Chimeric Antigen Receptor T Cells (B7-H3CART) in Recurrent Glioblastoma Multiforme
of adult subjects with recurrent IDH wild-type GBM using a standard 3+3 dose escalation design.
- 0 views
- 04 Oct, 2022
- 1 location
Functional and Ultrasound Guided Resection of Glioblastoma (FUTURE-GB)
Functional and ultrasound-guided resection of glioblastoma: assessing the use of additional imaging during surgery to improve outcomes for patients with glioblastoma brain tumours
- 0 views
- 18 Jun, 2022
- 17 locations
Feasibility of Individualized Therapy for Recurrent GBM
glioblastoma in a timely fashion. Collected tumor tissue and blood will be examined using a new diagnostic testing called University of California, San Francisco (UCSF) 500 Cancer Gene Panel which is done at
- 13 views
- 01 Feb, 2022
- 1 location
Individualized Systems Medicine Functional Profiling for Recurrent Glioblastoma
A study to determine the feasibility and safety of individualized cancer stem cell targeted therapy based on high-throughput functional profiling of FDA/EMA-approved drugs in patients with GBM
- 0 views
- 20 Sep, 2021
- 1 location
A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme
The current design provides a window to analyze the impact of the ACT001+Pembrolizumab combination on the tumor microenvironment and disease outcomes.
- 0 views
- 24 Nov, 2021