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Found 74 clinical trials
Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma (GLAUCALYX)

The glycocalyx is a fibrillary lining structure that covers the inner surface of blood vessels. Composed of glycoproteins and polysaccharides, it is an essential determinant of vascular endothelial physiology: it limits coagulation activation and adapts capillary perfusion. Studies have shown glycocalyx alteration in various vascular and autoimmune pathologies such as …

primary open angle glaucoma
optic neuropathy
aqueous humor
diabetic retinopathy
  • 17 Jun, 2022
  • 1 location
Macular Pigment Optical Density in Primary Angle-closure Disease

Glaucoma is the leading cause of irreversible blindness in the world, and primary angle-closure glaucoma (PACG) is the most important type of glaucoma in Asia. Primary angle closure disease (PACD) is a group of diseases related to PACG, and the pathogenesis is still unclear. Macular pigment has the functions of …

slit lamp examination
intraocular pressure
Accepts healthy volunteers
  • 10 Mar, 2022
  • 1 location
MINIject Global Long-Term Follow-up Study

The study will assess the long-term (up to 5 years) safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.

glaucoma surgery
brimonidine tartrate ophthalmic solution
  • 22 Dec, 2021
  • 1 location
Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma.

This study is to characterize mitochondrial DNA (mtDNA) populations in adults with eye injuries and eye diseases. The eye exam is often hindered by the clouding of tissues involved in injury or disease. This protocol examines the use of mtDNA populations as indicators of developing inflammation and resolution of injury. …

eye exam
macular degeneration
diabetic retinopathy
eye disease
age-related macular degeneration
  • 04 Oct, 2022
  • 1 location