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Found 119 clinical trials
Latanoprost Preserved Versus Unpreserved: Effect on Tear Film Thickness as Measured With OCT

Topical antihypertensive eye drops are a key element of modern antiglaucoma treatment. Most of these eye drops contain preservatives to allow for the use of multi-dose containers. In the recent years evidence has, however, accumulated that these preservatives may induce ocular surface disease (OSD). This is particularly true for the …

primary open angle glaucoma
latanoprost
optical coherence tomography
benzalkonium chloride
glaucoma
  • 18 views
  • 21 Apr, 2022
  • 1 location
Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear

The purpose of this study is to determine if short-term wear of a spherical rigid contact lens, called a scleral lens, will raise intraocular pressure in ocular hypertensive patients.

brimonidine tartrate ophthalmic solution
intraocular pressure
glaucoma
cataract
  • 10 views
  • 19 Apr, 2022
  • 1 location
Effect of Intraocular Tamponade on Visual Function in the Human Eyes

Intraocular tamponade used in vitrectomy operations may affects retinal function in various mechanisms.

  • 0 views
  • 11 Oct, 2022
  • 1 location
A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing Orientation and Mobility Training

In this study, the study team utilize virtual reality (VR) to simulate visual impairments of different types and severity in healthy subjects. The platform implements three of the most widespread forms of visual impairment in the United States (US): age-related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma, each with …

diabetic retinopathy
Accepts healthy volunteers
glaucoma
brimonidine tartrate ophthalmic solution
retinopathy
  • 0 views
  • 28 Oct, 2022
  • 1 location
A Clinical Study to Evaluate the Efficacy and Safety of CKD-351

The purpose of this study is to evaluate efficacy and safety of CKD-351

primary open angle glaucoma
latanoprost
hypertension
glaucoma
brimonidine tartrate ophthalmic solution
  • 88 views
  • 25 Jan, 2021
BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension

The purpose of this study is to evaluate the clinical efficacy of the BREMEN eye drops in the treatment of primary open-angle glaucoma or intraocular hypertension.

hypertension
intraocular pressure
glaucoma
combigan
  • 4 views
  • 04 Oct, 2022
  • 1 location
Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects

neural function. The investigators seek to measure neurovascular coupling in the human retina in patients with early primary open angle glaucoma (POAG), normal tension glaucoma, ocular

primary open angle glaucoma
normal tension glaucoma
glaucoma
visual field tests
hypertension
  • 6 views
  • 20 Apr, 2022
  • 1 location
The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis

The Boston keratoprosthesis (KPro) is a special plastic device that is used to replace a sick cornea (transparent part of the eye, in front of the iris) in order to restore vision in patients who have failed traditional corneal transplants or have a very poor prognosis of success. Glaucoma is …

optic nerve injury
optic nerve damage
glaucoma
visual field tests
brimonidine tartrate ophthalmic solution
  • 0 views
  • 04 Feb, 2021
  • 1 location
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Eye Diseases

This trial will study the safety and efficacy of intravenous and sub-tenon delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Eye diseases

eye disease
other disease
brimonidine tartrate ophthalmic solution
  • 0 views
  • 22 Oct, 2022
  • 1 location
Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo) (KPro-HP-Endo)

Common complications of the Boston keratoprosthesis type 1 (KPro) surgery include retroprosthetic membrane formation, glaucoma, and retinal detachment. Often pars plana vitrectomy (PPV) is performed at the same time as KPro surgery for different indications. It has been shown to reduce postoperative complications in comparison to when it is performed …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location