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Found 116 clinical trials
Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance

Glaucoma is a major cause of blindness. The inability to predict a patient's IOP response to medications is a critical barrier for the clinician to consistently provide highly effective IOP-based treatments. Current trial-and-error approaches to glaucoma management are inefficient and have not addressed this barrier as there are no predictive …

latanoprost 0.005% eye drops
latanoprost
pigmentary glaucoma
brimonidine tartrate ophthalmic solution
ophthalmic solution
  • 0 views
  • 04 Oct, 2022
  • 3 locations
Optic Nerve Head Structural Response to IOP Elevation in Patients With Keratoconus

The mechanism by which vision loss in glaucoma occurs is still unknown, but it is clear that increased Intraocular Pressure (IOP) is a major risk factor. It is also thought that the lamina cribrosa (LC) is a site of primary damage during the pathogenesis of the disease. The changes caused …

glaucoma
slit lamp examination
brimonidine tartrate ophthalmic solution
neuropathy
blindness
  • 0 views
  • 23 Apr, 2022
  • 1 location
Glaucoma Surgery Using the ViaLase Femtosecond Laser

Prospective, single-center, multi-cohort clinical trial of ViaLase Laser for the reduction of IOP in patients with open angle glaucoma.

glaucoma surgery
glaucoma
brimonidine tartrate ophthalmic solution
  • 0 views
  • 02 Oct, 2021
  • 1 location
Training of Eye Movements in Glaucoma

The aim of the trial is to investigate the possibilities of improving visual impairments with eye training exercises (eye-yoga) in a total of 40 patients with glaucoma who have not previously been treated within a similar training program. 20 patients will be instructed how to do eye yoga to be …

  • 0 views
  • 15 Feb, 2021
  • 2 locations
Efficacy and Necessity of Time Interval Between Instillation of Two Glaucoma Eye Drops

According to the American Academy of Ophthalmology's Preferred Practice Pattern on Primary Open Angle Glaucoma, patients should wait five minutes between administering topical drops for intra-ocular pressure reduction. To date, no study has shown the efficacy of this waiting period. In this study, we aim to establish the clinical significance …

brimonidine tartrate ophthalmic solution
primary open angle glaucoma
beta blockers
brimonidine/timolol
glaucoma
  • 0 views
  • 10 Oct, 2021
  • 1 location
Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery (SUSTAIN)

In this study, the investigators are comparing dexamethasone ophthalmic insert (DEXTENZA®) to the current standard of care, prednisolone acetate 1% eye drops, in a glaucoma population receiving both cataract and minimally-invasive glaucoma surgery (MIGS). DEXTENZA® and prednisolone acetate 1% drops are both steroids used to control inflammation after eye surgery. …

cataract
brimonidine tartrate ophthalmic solution
dexamethasone
prednisolone
ophthalmic solution
  • 1 views
  • 06 Apr, 2022
  • 1 location
Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients

The main study purpose is to demonstrate the non-inferiority of T4032 compared to Lumigan® 0.01% in terms of efficacy.

hypertension
glaucoma
bimatoprost
lumigan
  • 0 views
  • 04 Oct, 2022
  • 1 location
Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients.

The study purpose is to evaluate the safety of T4090.

hypertension
glaucoma
  • 0 views
  • 04 Oct, 2022
  • 1 location
Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery (TRICEPS)

During glaucoma surgery, a new opening is created that allows fluid to drain out of the eye, bypassing the clogged drainage channels that are malfunctioning in patients with glaucoma. In some patients who have had glaucoma surgery too much fluid flows out and this results in a pressure that is …

brimonidine tartrate ophthalmic solution
ophthalmic solution
drainage
glaucoma
treatment of glaucoma
  • 2 views
  • 13 May, 2022
  • 1 location
Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-1)

This prospective, single-arm clinical multicenter study intends to measure normal structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the macula using the Heidelberg Spectralis OCT device. This study is conducted in African-American descent volunteers. The main goal of the study is to provide the …

cataract
neuropathy
corrected visual acuity
intraocular pressure
diabetic retinopathy
  • 1 views
  • 12 May, 2022
  • 1 location