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Found 121 clinical trials
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A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

intraocular pressure
glaucoma
  • 4 views
  • 10 Mar, 2022
  • 1 location
Clarifying the Optimal Application of SLT Therapy Trial (COAST)

The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting …

  • 0 views
  • 21 Jul, 2022
  • 13 locations
Efficacy and Safety Assessment of T4030 Eye Drops Versus Ganfort UD in Ocular Hypertensive or Glaucomatous Patients.

To demonstrate the non-inferiority of T4030 unpreserved eye drops compared to Ganfort UD in terms of efficacy.

  • 4 views
  • 31 May, 2021
  • 1 location
Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes (STACCATO)

Cytomegalovirus (CMV) is generally a latent and asymptomatic infection in healthy, immunocompetent individuals. In immunocompromised patients CMV is well known to cause a retinitis that can lead to blindness. In immunocompetent patients, however, CMV can cause recurrent inflammation in the front of the eye (anterior uveitis). CMV anterior uveitis produces …

  • 18 views
  • 24 Jul, 2022
  • 1 location
A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

This is a randomized, Investigator-masked, multi-center, parallel group, therapeutic equivalence study with clinical endpoint.

ocular hypotensive
hypotensive
glaucoma
hypertension
azopt
  • 8 views
  • 09 Jul, 2022
  • 29 locations
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali)

The objective of this clinical study is to evaluate the safety and efficacy of NCX 470 Ophthalmic Solution in lowering intraocular pressure (IOP) in subjecs with ocular hypertension or open

glaucoma
corrected visual acuity
ophthalmic solution
intraocular pressure
latanoprost
  • 0 views
  • 10 May, 2022
  • 1 location
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.

Evaluate the safety and effectiveness of iSTAR Medical's MINIject implant for lowering intraocular pressure (IOP) in subjects with primary open-angle glaucoma.

glaucoma surgery
medical therapy
glaucoma
intraocular pressure
filtration surgery
  • 0 views
  • 04 Sep, 2021
  • 1 location
The Glaucoma Nicotinamide Trial (TGNT)

The Glaucoma Nicotinamide Trial (TGNT) is a prospective, randomized, placebo-controlled double-masked clinical trial composed of two cohorts; The Swedish Glaucoma Nicotinamide Trial (SGNT) and the Vitamin B3 In Glaucoma Study (VBIGS). Patients with open-angle glaucoma (OAG) will be randomized to receive either Nicotinamide or placebo through block randomization stratified by …

laser trabeculoplasty
glaucoma
trabeculectomy
tension
corrected visual acuity
  • 0 views
  • 19 Jun, 2022
  • 2 locations
Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

glaucoma (OAG) or ocular hypertension (OHT) who are not adequately managed with topical IOP-lowering medication for reasons other than medication efficacy.

bimatoprost
glaucoma
pigmentary glaucoma
pseudoexfoliation glaucoma
intraocular pressure
  • 409 views
  • 22 Jul, 2022
  • 91 locations
Village-Integrated Eye Worker Trial II (VIEW II)

The vast majority of blindness is avoidable. The World Health Organization (WHO) estimates that 80% of cases of visual impairment could be prevented or reversed with early diagnosis and treatment. The leading causes of visual impairment are cataract and refractive error, followed by glaucoma, age-related macular degeneration (AMD), and diabetic …

glaucoma
visual loss
eye disorder
diabetic retinopathy
eye disease
  • 42 views
  • 10 Feb, 2022
  • 1 location