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Found 232 clinical trials
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Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-angle Glaucoma or Ocular Hypertension

glaucoma (OAG) or ocular hypertension (OHT) who are not adequately managed with topical IOP-lowering medication for reasons other than medication efficacy.  

bimatoprost
pseudoexfoliation glaucoma
intraocular pressure
hypertension
pigmentary glaucoma
  • 78 views
  • 10 Feb, 2021
  • 1 location
featured
DE-117 Spectrum 5 Study

Santen will evaluate the intraocular pressure (IOP) lowering effect and efficacy of DE-117 ophthalmic solution 0.002% in latanoprost/non-responder subjects diagnosed with POAG or OHT  

latanoprost
ophthalmic solution
glaucoma
intraocular pressure
corrected visual acuity
  • 69 views
  • 10 Feb, 2021
  • 1 location
featured
A Phase 3, Randomized, Multi-Regional, Double-Masked, Parallel-Group Trial Evaluating the Safety and Efficacy of NCX 470 0.1% vs. Latanoprost 0.005% in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali)

-angle glaucoma.Subjects will be randomized in a 1:1 ratio to NCX 470 0.1% or to latanoprost 0.005% to be administered to both eyes once daily in the evening for up to 12 months

latanoprost
ophthalmic solution
glaucoma
intraocular pressure
corrected visual acuity
  • 0 views
  • 10 Jun, 2021
  • 1 location
Safety and Effectiveness of the XEN45 Glaucoma Treatment System in Patients With Angle Closure Glaucoma

This study will evaluate the safety and IOP-lowering effectiveness of XEN in patients with Angle Closure Glaucoma.

  • 161 views
  • 18 Apr, 2021
  • 32 locations
Trabeculectomy Versus Canaloplasty to Treat Glaucoma

The aim of the study is to investigate pressure lowering effect of two surgical methods canaloplasty and trabeculectomy in patients with open angle glaucoma, in which under local pressure

mitomycin
ophthalmic solution
trabeculectomy
pigmentary glaucoma
  • 4 views
  • 07 Nov, 2020
  • 1 location
Instrument for Glaucoma Early Detection and Monitoring

To introduce a rapid and objective electrophysiological technique that can assess visual function in the magnocellular pathway, which is thought to be affected in early-stage glaucoma.

  • 114 views
  • 07 Nov, 2020
  • 3 locations
Ologen (OculusGen)-Glaucoma MMC Control Trial in India

The purpose of this study is to compare the safety and effectiveness of the ologen (OculusGen) Biodegradable Collagen Matrix Implant and the MMC group in filtration surgery.

trabeculectomy
filtration surgery
  • 22 views
  • 07 Nov, 2020
  • 1 location
Subconjunctival Bevacizumab to Prevent Bleb Failure After Glaucoma Filtration Surgery

This study analyzes the safety and efficacy of off-label Subconjunctival Injection of bevacizumab (Avastin) versus 0.02% mitomycin C (MMC) for preventing bleb failure following glaucoma

mitomycin
intraocular pressure
trabeculectomy
filtration surgery
medical therapy
  • 28 views
  • 07 Nov, 2020
  • 1 location
Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.

WHAT IS THIS STUDY ABOUT? Glaucoma and ocular hypertension are chronic eye diseases that can damage the optic nerve and lead to vision loss or blindness. The optic nerve acts like an

neuropathy
dorzolamide
intraocular pressure
trabeculectomy
xalatan
  • 24 views
  • 07 Nov, 2020
  • 1 location
Ocular Blood Flow in Early Glaucoma Patients Before and After Treatment With Dorzolamide

Impaired ocular blood flow is an important risk factor in the pathogenesis of primary open angle glaucoma (POAG). A few studies suggest that topical dorzolamide 2% may increase optic

neuropathy
dorzolamide
primary open angle glaucoma
corrected visual acuity
diabetic retinopathy
  • 65 views
  • 07 Nov, 2020
  • 1 location