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Found 5 clinical trials
Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders

The purpose of the trial is to evaluate the PK, bioavailability, PD, efficacy and safety of MarzAA for on demand treatment and control of bleeding episodes in adult subjects with inherited bleeding disorders.

  • 12 Mar, 2021
  • 19 locations
Anti- IIb 3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti- IIb 3 Antibodies Study (TAAS)

This project aim to correlate risk factors (genetic, therapeutic and socio-demographic factors) to anti-IIb3 antibodies formation following blood products transfusion (platelets or packed red cells) or pregnancy in a national cohort of GT patients.

  • 02 Feb, 2021
  • 8 locations
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

This is a study to collect the outcomes of stem cell transplantation for patients with hematologic diseases other than cancer.

cell transplantation
  • 26 Jan, 2021
  • 1 location
Fludarabine Phosphate Cyclophosphamide Total Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

This phase II trial studies how well fludarabine phosphate, cyclophosphamide, total body irradiation, and donor stem cell transplant work in treating patients with blood cancer. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the …

reduced intensity conditioning
white blood cells
lymphocytic leukemia
blood stem cell transplant
  • 24 Jan, 2021
  • 1 location
The Genetics and Functional Basis of Inherited Platelet White Blood Cell Red Blood Cell and Blood Clotting Disorders.

Blood contains red blood cells, white blood cells, and platelets, as well as a fluid portion termed plasma. We primarily study blood platelets, but sometimes we also analyze the blood of patients with red blood cell disorders (such as sickle cell disease), white blood cell disorders, and disorders of the …

  • 01 Feb, 2021
  • 1 location