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Found 1017 clinical trials
Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS

The majority of testicular cancer patients can be cured with cisplatin-based chemotherapy. Mortality has been reduced even more within the last 15 years due to the stringent application of standard chemotherapy followed by resection of residual disease. This is a positive development considering that testicular cancer usually affects young men. …

renal function tests
cardiovascular disease
  • 09 Aug, 2021
  • 1 location
Children and Adults With Chordoma

Background Chordoma is a rare type of bone cancer. It occurs in the skull base or spine. Researchers want to study people with chordoma in different ways. They hope this will help them design better future treatments and supportive care studies for this disease. Objective To learn more about chordoma …

ct scan
  • 27 Jul, 2022
  • 1 location
Prospective Study on Quality of Life in Patients With Intracranial Germ Cell Tumors

The primary purpose of this study is to characterize the quality of life in patients with intracranial germ cell tumors. Those findings can contribute towards a better understanding of the

  • 25 Nov, 2021
  • 1 location
Surveillance of Association of Immune Status and Prognosis of CNS Germ Cell Tumor Survivors

treatment for intracranial germ cell tumors. However, whether reliable clinical data can quantify the damage degree of immunologic function caused by chemotherapy and radiotherapy is still unknown. This

  • 12 Jun, 2021
  • 1 location
Long-Term Longitudinal QoL in Patients Undergoing EEA

This is a prospective longitudinal study to access postoperative 2-year quality of life in patients who undergo endonasal endoscopic approach surgeries of the skull base.

  • 28 Jun, 2021
  • 1 location
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas

Rationale: Chordomas and chondrosarcomas located in the axial skeleton are malignant neoplasms of bone. These tumors share the same clinical challenges, as the effect of the disease is more a function of their local aggressiveness than their tendency to metastasize (20% metastasize). The local aggressive behavior can cause debilitating morbidity …

proton therapy
  • 16 Apr, 2021
  • 2 locations
Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in Children

The aim of this study was to evaluate the diagnostic efficacy of computer aided diagnostic tool for retroperitoneal tumor using machine learning and deep learning techniques on computed tomography images in children.

  • 21 Mar, 2022
  • 1 location
Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)

This study aims to evaluate the prevalence, biological mechanism and survivorship impact of cognitive toxicity among adolescent and young adult (AYA) patients diagnosed with curable cancers. The hypothesis is that cognitive impairment is clinically significant among AYA cancer patients treated with chemotherapy and that there will be detectable structural and …

chemotherapy regimen
Accepts healthy volunteers
cancer chemotherapy
  • 13 Feb, 2022
  • 2 locations
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for the Management of Pelvic Sarcomas Involving the Bone, the PROSPER Study

This study compares carbon ion therapy, surgery, and proton therapy to determine if one has better disease control and fewer side effects. There are three types of radiation treatment used for pelvic bone sarcomas: surgery with or without photon/proton therapy, proton therapy alone, and carbon ion therapy alone. The purpose …

soft tissue sarcoma
cancer chemotherapy
proton therapy
  • 18 Jun, 2022
  • 3 locations
MicroRNA as Markers in Testicular Cancer

The main objective of this study is establish the performance of miR371 in management of testicular cancer

  • 13 Jun, 2021
  • 6 locations