Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 1020 clinical trials
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumor. The safety of combining G207 with a single low dose of radiation, designed to enhance virus replication, tumor cell killing, and an anti-tumor immune response, …

medulloblastoma
astrocytoma, anaplastic
glioblastoma multiforme
biological factors
myelosuppressive chemotherapy
  • 84 views
  • 18 Jun, 2022
  • 1 location
TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

A Phase 1 open label trial of intravenous administration of TAEK-VAC-HerBy vaccine in patients with advanced brachyury and/or HER2- expressing cancer. The study will be completed in 2 stages. In Stage 1 patients will be enrolled and treated according to a 3+3 dose escalation scheme. Up to 4 dose levels …

lung cancer
estrogen receptor
ct scan
pertuzumab
hormone therapy
  • 13 views
  • 27 Jun, 2022
  • 7 locations
Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have recurred or spread to other places in the body (advanced), lymphoma, or histiocytic disorders, that have a genetic alteration in the gene HRAS. Tipifarnib may block the growth of cancer cells …

cancer treatment
interferon
cns tumor
growth factor
match treatment
  • 28 views
  • 27 Jun, 2022
  • 91 locations
Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well ensartinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with ALK or ROS1 genomic alterations that have come back (recurrent) or do not respond to treatment (refractory) and have spread to other places in the body (advanced). …

cancer treatment
interferon
cns tumor
ensartinib
growth factor
  • 68 views
  • 29 Jun, 2022
  • 70 locations
Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well selpercatinib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphomas, or histiocytic disorders that have activating RET gene alterations. Selpercatinib may block the growth of cancer cells that have specific genetic changes …

cancer treatment
RET
cns tumor
interferon
growth factor
  • 18 views
  • 02 Jul, 2022
  • 91 locations
Pain and Quality of Life After Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS

Thoracoscopic assisted mediastinal thymectomy is currently one of the most commonly used surgical methods, but there are some deficiencies.Minimally invasive surgery through the subxiphoid approach can achieve a good surgical field of vision. (1) The surgical field is fully exposed. (2) damage to intercostal nerves can be avoided.(3) Operation time, …

video-assisted thoracic surgery
Accepts healthy volunteers
postoperative pain
  • 41 views
  • 26 May, 2022
  • 1 location
ETMR One: An International Registry and Research Platform for Children With Embryonal Tumor With Multilayer Rosettes

This research is being done to find out more information about a brain tumor called Embryonal Tumor with Multilayer Rosettes (ETMR) by collecting medical information from children who have this

  • 5 views
  • 18 Mar, 2021
  • 1 location
Study of Stored Tumor Samples in Young Patients With Brain Tumors

This laboratory study is looking at stored tumor samples in young patients with brain tumors. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

  • 3 views
  • 24 Apr, 2022
  • 1 location
Germ Cell Tumor and Testicular Tumor DNA Registry

This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also

cancer
Accepts healthy volunteers
testicular
testicular tumor
germ cell tumor
  • 49 views
  • 23 Apr, 2022
  • 6 locations
Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors

The purpose of this study is to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.

germ cell cancer
cancer
testicular
  • 18 views
  • 24 Jan, 2021
  • 1 location