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Found 1051 clinical trials
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ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT)

ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT)

  • 170 views
  • 08 Nov, 2020
  • 1 location
None
Gemcitabine Paclitaxel Ifosfamide and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors

with paclitaxel, ifosfamide, and cisplatin, and to see how well they work in treating patients with progressive or relapsed metastatic germ cell tumors.

filgrastim
pegfilgrastim
lenograstim
combination chemotherapy
germ cell tumor
  • 32 views
  • 07 Nov, 2020
  • 1 location
None
Sorafenib Monotherapy in Inoperable/Recurrent Germ Cell Carcinoma Refractory to Chemotherapy

Germ cell tumors, a relatively rare disease, but most common malignancy in young males, occur most frequently in testis. The incidence is about 1%, but is increasing in the majority of

carcinoma
oxaliplatin
sorafenib
germ cell tumor
measurable disease
  • 74 views
  • 07 Nov, 2020
  • 1 location
None
Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease

Comparative study on surgery versus definitive radiation therapy in primary localized sacral chordoma

ct scan
proton therapy
antineoplastic
  • 31 views
  • 09 Nov, 2021
  • 31 locations
None
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active

platelet count
beta human chorionic gonadotropin
immature teratoma
testicular
tumor cells
  • 349 views
  • 27 Oct, 2021
  • 374 locations
None
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, cisplatin, carboplatin, and etoposide

platelet count
stem cell transplantation
testicular
tumor cells
paclitaxel
  • 803 views
  • 24 Nov, 2021
  • 98 locations
None
A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.

program. METHOD: PASCA is a single-center, interventional cohort study of adult patients who received at least chemotherapy and with a complete remission to a testicular germ cell tumor, primary

  • 0 views
  • 16 Feb, 2021
  • 1 location
None
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcomes when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for …

pembrolizumab
immunomodulator
lung carcinoma
chemoradiotherapy
lung cancer
  • 27 views
  • 05 Jun, 2021
  • 82 locations
None
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphomas or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

platelet count
palbociclib
cytokines
myelosuppressive chemotherapy
autologous stem cell infusion
  • 997 views
  • 26 Nov, 2021
  • 114 locations
None
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

mucinous adenocarcinoma Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03/30/2018) Trophoblastic tumor: A

lipase
giant cell tumors
adrenaline
total bilirubin
solid tumors
  • 6055 views
  • 02 Dec, 2021
  • 820 locations